Evidence map›Paper›PMID 32690639›Full record

ArticleAntimicrobial agents and chemotherapy2020

Combination of Miconazole and Domiphen Bromide Is Fungicidal against Biofilms of Resistant

Jana Tits, Freya Cools, Kaat De Cremer, Katrijn De Brucker, Judith Berman, Kristof Verbruggen, Bert Gevaert, Paul Cos, Bruno P A Cammue, Karin Thevissen

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Review
  3. Distribution ofHealthcare (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Study on the impact of biofilm formation byFrontiers in cellular and infection microbiology · 2025
    Article
  6. New insights in the role ofFrontiers in microbiology · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Frontiers in microbiology · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Role of Antifungal Combinations in Difficult to TreatJournal of fungi (Basel, Switzerland) · 2021
    Review
  16. Article
  17. Combination Therapy to Treat Fungal Biofilm-Based Infections.International journal of molecular sciences · 2020
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Jana TitsCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Freya CoolsLaboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
Kaat De CremerCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Katrijn De BruckerCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Judith BermanDepartment of Molecular Microbiology and Biotechnology, School of Molecular Cell Biology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
Kristof VerbruggenPurna Pharmaceuticals, Puurs, Belgium.
Bert GevaertPurna Pharmaceuticals, Puurs, Belgium.
Paul CosLaboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
Bruno P A CammueCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.
Karin ThevissenCentre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium karin.thevissen@kuleuven.be.ORCID 0000-0003-0275-9072
KU Leuven · BEUniversity of Antwerp · BETel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The occurrence and recurrence of mucosal biofilm-related

Indexed as

CandidaMiconazoleAnimalsAntifungal AgentsBiofilmsCandida albicansFemaleHumansMicrobial Sensitivity TestsQuaternary Ammonium CompoundsRatsAntifungal AgentsdomiphenMiconazoleQuaternary Ammonium CompoundsbiofilmsCandidacombination treatmentdomiphen bromidedrug repurposingfungicidalmiconazoleresistance developmentvulvovaginal candidiasis

Identifiers

PMID32690639
PMCPMC7508569
OpenAlexW3042715998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.