Evidence map›Paper›PMID 32690635›Full record

ArticleInfection and immunity2020

Brucella abortus and Pregnancy in Mice: Impact of Chronic Infection on Fertility and the Role of Regulatory T Cells in Tissue Colonization.

Shakirat A Adetunji, Denise L Faustman, L Garry Adams, Daniel G Garcia-Gonzalez, Martha E Hensel, Omar H Khalaf, Angela M Arenas-Gamboa

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Osteomyelitis.Nature reviews. Disease primers · 2026
    Review
  2. Enhanced immunogenicity of theFrontiers in immunology · 2026
    Article
  3. Article
  4. International journal of molecular sciences · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Microorganisms · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Shakirat A AdetunjiDepartment of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-5352-3695
Denise L FaustmanMassachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
L Garry AdamsDepartment of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.
Daniel G Garcia-GonzalezDepartment of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.
Martha E HenselDepartment of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-8520-0279
Omar H KhalafDepartment of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.
Angela M Arenas-GamboaDepartment of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA aarenas@cvm.tamu.edu.
Texas A&M University · USHarvard University · USUniversity of Baghdad · IQ

Funding

Comparative Biomedical Research Training for VeterinariansT32OD011083 · OD · TEXAS A&M AGRILIFE RESEARCH · PI ALBERT MULENGA · 2012 to 2026
$4.8M
Use of the goat model to test human Brucella vaccines in ArgentinaK01TW009981 · FIC · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ARENAS, ANGELA M · 2014 to 2018
$670k
FIC NIH HHS K01 TW009981NIH HHS T32 OD011083
6 · The paper itself

Abstract

Stealthy intracellular bacterial pathogens are known to establish persistent and sometimes lifelong infections. Some of these pathogens also have a tropism for the reproductive system, thereby increasing the risk of reproductive disease and infertility. To date, the pathogenic mechanism involved remains poorly understood. Here, we demonstrate that

Indexed as

Acute DiseaseAnimalsBacterial LoadBrucella abortusBrucellosisChronic DiseaseFemaleFertilityMiceMice, Inbred ICRPregnancyPregnancy Complications, InfectiousReceptors, Tumor Necrosis Factor, Type IISpleenT-Lymphocytes, RegulatoryUterusReceptors, Tumor Necrosis Factor, Type IIantagonismantibodyBrucellaregulatory T cellsTNFR2tropism

Identifiers

PMID32690635
PMCPMC7504963
OpenAlexW3043248561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.