Evidence map›Paper›PMID 32690633›Full record

ArticleInfection and immunity2020

Diffusible Signal Factors Act through AraC-Type Transcriptional Regulators as Chemical Cues To Repress Virulence of Enteric Pathogens.

Erick Maosa Bosire, Colleen R Eade, Carl J Schiltz, Amanda J Reid, Jerry Troutman, Joshua S Chappie, Craig Altier

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 39 citations in OpenAlex.

  1. Gut microbes · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. A recombinant lysogenic bacteriophage inhibitsAntimicrobial agents and chemotherapy · 2026
    Article
  7. mBio · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Fisetin inhibitsMicrobiology spectrum · 2024
    Article
  13. Review
  14. Gut microbes · 2023
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Erick Maosa BosireDepartment of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA ebm82@cornell.edu.ORCID 0000-0002-1804-244X
Colleen R EadeDepartment of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.ORCID 0000-0002-1009-0420
Carl J SchiltzDepartment of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Amanda J ReidDepartment of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.
Jerry TroutmanDepartment of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.
Joshua S ChappieDepartment of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Craig AltierDepartment of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Cornell University · USUniversity of North Carolina at Charlotte · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Successful colonization by enteric pathogens is contingent upon effective interactions with the host and the resident microbiota. These pathogens thus respond to and integrate myriad signals to control virulence. Long-chain fatty acids repress the virulence of the important enteric pathogens

Indexed as

AnimalsAraC Transcription FactorBacterial ProteinsFatty Acids, UnsaturatedFatty Acid Transport ProteinsGene Expression Regulation, BacterialGenomic IslandsIntestinesMicePalmitic AcidsProtein BindingProtein StabilitySalmonella InfectionsSalmonella typhimuriumSignal TransductionTranscription FactorsAraC Transcription FactorBacterial ProteinsFatty Acids, UnsaturatedFatty Acid Transport Proteinshexadecenoic acidHilD protein, Salmonella typhimuriumPalmitic AcidsTranscription Factorsdiffusible signal factorsfatty acidsgene expressionhost cell invasiontranscriptional regulationvirulence regulation

Identifiers

PMID32690633
PMCPMC7504960
OpenAlexW3042309938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.