ArticleGut2021
Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study.
Abstract readLetterComment
In one paragraph
Article in Gut, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 5 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 5 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Grading the evidence for the association between periodontal disease and chronic non-communicable diseases: an umbrella review of meta-analyses of observational studies.BMC oral health · 2026Pooled it
- Tooth loss and infrequent brushing significantly elevate gastric cancer risk: an updated systematic review and meta-analysis with heterogeneity exploration.Frontiers in medicine · 2026Pooled it
- The efficacy of lactic acid bacteria-based toothpaste on oral health: a systematic review and meta-analysis.Frontiers in oral health · 2025Pooled it
- Gastric adenocarcinoma and periodontal disease: A systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2024Pooled it
- Gut microbiome alterations during gastric cancer: evidence assessment of case-control studies.Frontiers in microbiology · 2024Pooled it
- The evolving landscape of CDK inhibitor use in breast cancer therapy and beyond.Nature reviews. Drug discovery · 2026Review
- Oral Environment of Esophageal Cancer Patients, the Incidence of Complications, and Long-Term Prognoses.Current oncology (Toronto, Ont.) · 2026Review
- Longitudinal analysis of postoperative chemotherapy on oral-gut microbiota in patients with advanced gastric cancer.BMC microbiology · 2026Article
- The Balance and Imbalance of Microbial Communities: Oral-Gut Microbiota and Colorectal Cancer.American journal of clinical oncology · 2025Review
- Periodontal Status and Gingival Crevicular FluidJournal of clinical medicine · 2025Article
- New advances in oral microbiology and tumor research.World journal of clinical oncology · 2025Review
- Article
- Microbiome, metabolome, and transcriptome analyses in esophageal squamous cell carcinoma: insights into immune modulation by F. nucleatum.Protein & cell · 2025Article
- Helicobacter pylori, microbiota and gastric cancer - principles of microorganism-driven carcinogenesis.Nature reviews. Gastroenterology & hepatology · 2025Review
- Association between periodontitis and gastrointestinal cancer risk and prognosis: evidence from a nested case-control study in Southwest China.European journal of medical research · 2025Article
- Practice and challenge of age-friendly functional restoration of stomatognathic system based on the strategy of functional tooth loss.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025Article
- The dynamic oral-gastric microbial axis connects oral and gastric health: current evidence and disputes.NPJ biofilms and microbiomes · 2025Review
- Causal Gene Identification and Biomarker Prioritization in Periodontitis via Integrative Multiomics and Mendelian Randomization.Mediators of inflammation · 2025Article
- Periodontal disease and gastric and colorectal cancers: mechanisms and therapeutic perspectives.Frontiers in cellular and infection microbiology · 2025Review
- Association Between Oral Health and Gastric Cancer in Korean Adults.The Korean journal of helicobacter and upper gastrointestinal research · 2024Article
Corrections and comments
- Comment on
Authors and funding
12 authors.
Chun-Han LoDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0001-8202-4513
Sohee KwonDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Liang WangDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Georgios PolychronidisDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Markus D KnudsenDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Rong ZhongDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Yin CaoDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri, USA.ORCID 0000-0001-9835-7662
Kana WuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Shuji OginoDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0002-3909-2323
Edward L GiovannucciDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Andrew T ChanDivision of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Mingyang SongDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA mis911@mail.harvard.edu.ORCID 0000-0002-1324-0316
Funding
Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI TWOROGER, SHELLEY S · 2000 to 2019
$77.8MValidity of Diet and Activity Measures in WomenP01CA055075 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI WILLETT, WALTER C. · 1991 to 2009
$41.8MLong Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3MCancer Epidemiology Cohort in Male Health ProfessionalsU01CA167552 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Lorelei Mucci, Walter C. Willett · 2017 to 2026
$17.0MPrecision Prevention Research ProgramR35CA253185 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Andrew T Chan · 2020 to 2026
$6.9MInflammation and Colorectal NeoplasiaR01CA137178 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHAN, ANDREW T · 2009 to 2019
$6.5MAccelerating Transdisciplinary Epidemiology of Colorectal CancerR35CA197735 · NCI · DANA-FARBER CANCER INST · PI OGINO, SHUJI · 2015 to 2021
$6.0MDietary sulfur, the gut microbiome, and colorectal cancerR01CA202704 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHAN, ANDREW T, GARRETT, WENDY S. · 2016 to 2020
$2.8MEpigenetic Events and Colorectal Cancer EpidemiologyR01CA151993 · NCI · DANA-FARBER CANCER INST · PI OGINO, SHUJI · 2010 to 2014
$2.6MMentored Patient-Oriented Research in Digestive DiseasesK24DK098311 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHAN, ANDREW T · 2013 to 2017
$930kMarine Omega-3 Polyunsaturated Fatty Acid, Gut Microbiome, and Colorectal Cancer PreventionR00CA215314 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI SONG, MINGYANG · 2018 to 2020
$679kOptimizing the Impact of Aspirin for ChemopreventionK07CA218377 · NCI · WASHINGTON UNIVERSITY · PI CAO, YIN · 2018 to 2021
$504kNCI NIH HHS K07 CA218377NCI NIH HHS P01 CA055075NCI NIH HHS P01 CA087969NCI NIH HHS R00 CA215314NCI NIH HHS R01 CA137178NCI NIH HHS R01 CA151993NCI NIH HHS R01 CA202704NCI NIH HHS R03 CA197879NCI NIH HHS R21 CA222940NCI NIH HHS R21 CA230873NCI NIH HHS R35 CA197735NCI NIH HHS R35 CA253185NCI NIH HHS U01 CA167552NCI NIH HHS UM1 CA186107NIAAA NIH HHS R21 AA027608NIDDK NIH HHS K24 DK098311
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdenocarcinomaStomach NeoplasmsTooth LossHumansProspective Studiesgastric canceroesophageal cancer
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.