Evidence map›Paper›PMID 32690584›Full record

ArticleG3 (Bethesda, Md.)2020

Identification of New Regulators of the Oocyte-to-Embryo Transition in

Emir E Avilés-Pagán, Albert S W Kang, Terry L Orr-Weaver

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Emir E Avilés-PagánDepartment of Biology, MIT, 77 Mass Avenue, Cambridge MA 02138.ORCID 0000-0003-1245-0941
Albert S W KangWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge MA 02142.
Terry L Orr-WeaverDepartment of Biology, MIT, 77 Mass Avenue, Cambridge MA 02138 weaver@wi.mit.edu.ORCID 0000-0002-7934-111X
Whitehead Institute for Biomedical Research · USIIT@MIT · US

Funding

REPLICATION AND POLYTENIZATION IN DROSOPHILA DEVELOPMENTR01GM039341 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI ORR-WEAVER, TERRY L. · 1993 to 2013
$4.7M
Producing, provisioning, and protecting the egg: Regulation of DNA replication, mRNA translation, and proteolysis for the transition from oocyte to embryoR35GM118098 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI ORR-WEAVER, TERRY L. · 2016 to 2018
$2.0M
NIGMS NIH HHS R01 GM039341NIGMS NIH HHS R35 GM118098
6 · The paper itself

Abstract

At the oocyte-to-embryo transition the highly differentiated oocyte arrested in meiosis becomes a totipotent embryo capable of embryogenesis. Oocyte maturation (release of the prophase I primary arrest) and egg activation (release from the secondary meiotic arrest and the trigger for the oocyte-to-embryo transition) serve as prerequisites for this transition, both events being controlled posttranscriptionally. Recently, we obtained a comprehensive list of proteins whose levels are developmentally regulated during these events via a high-throughput quantitative proteomic analysis of

Indexed as

DrosophilaDrosophila melanogasterAnimalsFemaleMeiosisOocytesOogenesisProteomicsembryogenesisF-box proteinglucose transportermitosisoogenesis

Identifiers

PMID32690584
PMCPMC7466974
OpenAlexW3045483406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.