ArticleBMJ open diabetes research & care2020
Children with type 1 diabetes have elevated high-sensitivity C-reactive protein compared with a control group.
Article in BMJ open diabetes research & care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 31 citations in OpenAlex.
- Relationship Between hsCRP, Glycaemic Control and Response to Sotagliflozin in Type 1 Diabetes: A Post Hoc Analysis of the inTandem3 Trial.Diabetes, obesity & metabolism · 2026Article
- Trace elements in relation to glycemic control and disease complications in children living with type 1 diabetes mellitus.Journal of clinical biochemistry and nutrition · 2026Article
- Echocardiography and inflammatory biomarkers for predicting mortality and major adverse cardiovascular events in type 1 diabetes.Cardiovascular diabetology · 2026Article
- Beyond HbAFrontiers in endocrinology · 2026Review
- Authors' Reply to Fatima Comment on "Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study".Paediatric drugs · 2025Article
- Effect of carvacrol on diabetes-induced oxidative stress, fibrosis and apoptosis in testicular tissues of adult rats.Physiological research · 2025Article
- Young Healthy Individuals With a First-Degree Relative With Type 1 Diabetes Displayed Adverse Lipid Changes.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Evaluation of Serum Soluble Lectin-like Oxidised Low-Density Lipoprotein Receptor-1 (sLOX-1) Level in Children with Non-Complicated Type-1 Diabetes Mellitus (T1DM) and Its Relationship with Carotid Intima Media Thickness (cIMT).Journal of clinical medicine · 2025Article
- An analysis of epidemiological characteristics of microvascular complications and comorbidities among type 1 diabetes patients.Acta biochimica Polonica · 2025Article
- Remnant Cholesterol Inflammatory Index and New-Onset Diabetes in Middle-Aged and Older Adults: Evidence From Prospective Surveys of Chinese and UK Populations.Journal of diabetes research · 2025Article
- Glycoprotein Acetyls Associate With Intraglomerular Hemodynamic Dysfunction, Albuminuria, Central Adiposity, and Insulin Resistance in Youth With Type 1 Diabetes.Canadian journal of diabetes · 2024Article
- The Mediterranean Diet for Adolescents with Type 1 Diabetes: A Prospective Interventional Study.Nutrients · 2023Article
- C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians.Diseases (Basel, Switzerland) · 2023Review
- Disease Duration and Chronic Complications Associate With Immune Activation in Individuals With Longstanding Type 1 Diabetes.The Journal of clinical endocrinology and metabolism · 2023Article
- Early Markers of Atherosclerosis in Children and Adolescents with Type 1 Diabetes Mellitus.Indian journal of pediatrics · 2023Article
- Laboratory Findings in Children with Excess Body Weight in Romania.Medicina (Kaunas, Lithuania) · 2023Article
- The Effect of Metabolic Profile on Leptin, Adiponectin, and hs-CRP in Children and Adolescents with Type 1 Diabetes.Children (Basel, Switzerland) · 2022Article
- Determination of CRP blood level in type 1 diabetic patients and the effect of aerobic and resistance training on the level of this biomarker.Caspian journal of internal medicine · 2022Article
- Relationship between lipid profile, inflammatory and endothelial dysfunction biomarkers, and type 1 diabetes mellitus: a case-control study.American journal of translational research · 2022Article
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8 authors at 1 institution in 1 country.
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Abstract
introductionOur objective was to compare high-sensitivity C-reactive protein (hsCRP) levels in children with type 1 diabetes, healthy controls, and children with obesity. Additionally, we aimed to analyze the association between hsCRP levels and glycemic control measured by glycohemoglobin A (HbA1c) and anthropometric and biochemical variables. RESEARCH DESIGN AND
methodsWe conducted a non-randomized descriptive study of children with type 1 diabetes matched for sex and age with a control group and group with obesity. We recorded anthropometric parameters and studied variables related to diabetes, blood pressure, lipid profile, and HbA1c. hsCRP was measured by ELISA.
resultsWe included 49 children with type 1 diabetes, 46 controls, and 40 children with obesity. hsCRP levels were significantly higher in the group with type 1 diabetes compared with controls and nearly significantly lower than in the group comprising children with obesity. We found no correlation between hsCRP and HbA1c and characteristics of type 1 diabetes with the exception of albumin to creatinine ratio. Statistically significant association was found between hsCRP and body mass index (BMI) and waist circumference Z-score.
conclusionsThe higher hsCRP levels observed in children with type 1 diabetes compared with a control group with a similar BMI suggest a basal inflammatory state that could increase cardiovascular risk. The main factors related to hsCRP are BMI and waist circumference, so obesity prevention should be a priority when performing follow-up in children with type 1 diabetes.
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