Evidence map›Paper›PMID 32690537›Full record

ArticleBMJ open2020

Cohort profile: BIOVASC-late, a prospective multicentred study of imaging and blood biomarkers of carotid plaque inflammation and risk of late vascular recurrence after non-severe stroke in Ireland.

John Joseph McCabe, Nicola Giannotti, Jonathan McNulty, Sean Collins, Sarah Coveney, Sean Murphy, Mary Barry, Joseph Harbison, Simon Cronin, David Williams and 9 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

John Joseph McCabeHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland mccabej1@tcd.ie.ORCID 0000-0003-2029-1303
Nicola GiannottiRadiography & Diagnostic Imaging, School of Medicine, University College Dublin, Dublin, Ireland.
Jonathan McNultyRadiography & Diagnostic Imaging, School of Medicine, University College Dublin, Dublin, Ireland.
Sean CollinsHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Sarah CoveneyHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Sean MurphyHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Mary BarryVascular Surgery, St Vincent's University Hospital, Dublin, Ireland.
Joseph HarbisonHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Simon CroninHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
David WilliamsHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Gillian HorganHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Eamon DolanHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Tim CassidyHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Ciaran McDonnellDepartment of Vascular Surgery, Mater Misericordiae University Hospital, Dublin, Ireland.
Eoin KavanaghDepartment of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland.
Shane FoleyRadiography & Diagnostic Imaging, School of Medicine, University College Dublin, Dublin, Ireland.
Martin O'ConnellDepartment of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland.
Michael MarnaneHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Peter KellyHealth Research Board Stroke Clinical Trials Network Ireland (HRB SCTNI), Dublin, Ireland.
Mater Misericordiae University Hospital · IEHealth Research Board · IEUniversity College Dublin · IEConnolly Hospital Blanchardstown · IECork University Hospital · IESt. Vincent's University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInflammation is important in stroke. Anti-inflammatory therapy reduces vascular events in coronary patients.

participantsThe Biomarkers Imaging Vulnerable Atherosclerosis in Symptomatic Carotid disease (BIOVASC) study and Dublin Carotid Atherosclerosis Study (DUCASS) are two prospective multicentred observational cohort studies, employing near-identical methodologies, which recruited 285 patients between 2008 and 2016 with non-severe stroke/transient ischaemic attack and ipsilateral carotid stenosis (50%-99%). Patients underwent coregistered carotid FINDINGS TO DATE: We have reported that FUTURE PLANS: The primary aim of BIOVASC-Late is to investigate the association between SUV

Indexed as

Brain IschemiaPlaque, AtheroscleroticStrokeAgedBiomarkersCarotid StenosisFemaleFluorodeoxyglucose F18Follow-Up StudiesHumansInflammationIrelandMalePositron-Emission TomographyPositron Emission Tomography Computed TomographyProspective StudiesBiomarkersFluorodeoxyglucose F18RadiopharmaceuticalsTissue Plasminogen Activatoradult neurologycardiovascular imagingpreventive medicinestroke

Identifiers

PMID32690537
PMCPMC7371237
OpenAlexW3044708446

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.