ArticleBMJ open2020
Multimorbidity patterns in low-middle and high income regions: a multiregion latent class analysis using ATHLOS harmonised cohorts.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Preoperative pathways in adults with multiple long-term conditions undergoing major surgery: a systematic review.BMJ open · 2026Pooled it
- Social determinants of multimorbidity patterns: A systematic review.Frontiers in public health · 2023Pooled it
- [Associations between multimorbidity patterns and depressive symptoms among middle-aged and older adults: a latent class analysis based on CHARLS data].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026Article
- Article
- Longitudinal pattern of multimorbidity in older adult population: latent transition analysis in 34 countries.American journal of epidemiology · 2026Article
- Identifying health risk profiles among older adults in Kerala using machine learning: multidimensional clustering, predictive determinants, and public health implications.Frontiers in public health · 2026Article
- Inequalities in multimorbidity between native-born and immigrant older adults across Europe.European journal of ageing · 2025Article
- Multimorbidity in dementia: Current perspectives and future challenges.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Spatial Analysis of patterns of Multimorbidity in the Thai Cohort Study Using Latent Class Analysis.Journal of epidemiology and global health · 2025Article
- Article
- Multimorbidity patterns and function among adults in low- and middle-income countries: a scoping review.BMJ open · 2025Article
- Sex- and age-specific multimorbidity networks in middle-aged inpatients: a network-based comparative study between China and the United Kingdom.Innovation in aging · 2025Article
- Chronic disease and multimorbidity in the Chinese older adults' population and their impact on daily living ability: a cross-sectional study of the Chinese Longitudinal Healthy Longevity Survey (CLHLS).Archives of public health = Archives belges de sante publique · 2024Article
- Multimorbidity patterns and disability and healthcare use in Europe: do the associations change with the regional socioeconomic status?European journal of ageing · 2024Article
- Impact of intensive hypertension criteria on multimorbidity prevalence and patterns in a multi-ethnic Chinese population.Frontiers in public health · 2024Article
- The effect of multimorbidity patterns on physical and cognitive function in diabetes patients: a longitudinal cohort of middle-aged and older adults in China.Frontiers in aging neuroscience · 2024Article
- Healthy immigrants, unhealthy ageing? Analysis of health decline among older migrants and natives across European countries.SSM - population health · 2023Article
- Topic modeling identifies novel genetic loci associated with multimorbidities in UK Biobank.Cell genomics · 2023Article
- Sociodemographic and lifestyle determinants of multimorbidity among community-dwelling older adults: findings from 346,760 SHARE participants.BMC geriatrics · 2023Article
- Spatial patterns in sociodemographic factors explain to a large extent the prevalence of hypertension and diabetes in Aragon (Spain).Frontiers in medicine · 2023Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesOur aim was to determine clusters of non-communicable diseases (NCDs) in a very large, population-based sample of middle-aged and older adults from low- and middle-income (LMICs) and high-income (HICs) regions. Additionally, we explored the associations with several covariates.
designThe total sample was 72 140 people aged 50+ years from three population-based studies (English Longitudinal Study of Ageing, Survey of Health, Ageing and Retirement in Europe Study and Study on Global Ageing and Adult Health) included in the Ageing Trajectories of Health: Longitudinal Opportunities and Synergies (ATHLOS) project and representing eight regions with LMICs and HICs. Variables were previously harmonised using an ex-post strategy. Eight NCDs were used in latent class analysis. Multinomial models were made to calculate associations with covariates. All the analyses were stratified by age (50-64 and 65+ years old).
resultsThree clusters were identified: 'cardio-metabolic' (8.93% in participants aged 50-64 years and 27.22% in those aged 65+ years), 'respiratory-mental-articular' (3.91% and 5.27%) and 'healthy' (87.16% and 67.51%). In the younger group, Russia presented the highest prevalence of the 'cardio-metabolic' group (18.8%) and England the 'respiratory-mental-articular' (5.1%). In the older group, Russia had the highest proportion of both classes (48.3% and 9%). Both the younger and older African participants presented the highest proportion of the 'healthy' class. Older age, being woman, widowed and with low levels of education and income were related to an increased risk of multimorbidity. Physical activity was a protective factor in both age groups and smoking a risk factor for the 'respiratory-mental-articular'.
conclusionMultimorbidity is common worldwide, especially in HICs and Russia. Health policies in each country addressing coordination and support are needed to face the complexity of a pattern of growing multimorbidity.
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