ArticleAmerican journal of preventive medicine2020
Adverse Childhood Experiences and Decreased Renal Function: Impact on All-Cause Mortality in U.S. Adults.
Article in American journal of preventive medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Maternal Separation and Negative Renal Programming, Evidence of Morphofunctional Alterations in Rodent Models: Systematic Review and Meta-Analysis.International journal of molecular sciences · 2025Pooled it
- Global Prevalence of Childhood Exposure to Physical Violence within Domestic and Family Relationships in the General Population: A Systematic Review and Proportional Meta-Analysis.Trauma, violence & abuse · 2024Pooled it
- Biopsychosocial Correlates of Somatic Symptom Burden in CKD: Results of the Hamburg City Health Study.Kidney360 · 2026Article
- Impact of adverse childhood experiences on kidney health.Pediatric nephrology (Berlin, Germany) · 2026Article
- The association of adverse childhood experiences with the progression of chronic kidney disease in children: a CKiD pilot study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Association between adverse childhood experiences with chronic kidney diseases in middle-aged and older adults in mainland China.Scientific reports · 2025Article
- The mediating effect of depressive syndrome on the relationship between adverse childhood experiences and chronic kidney diseases among middle-aged and older adults.Frontiers in public health · 2025Article
- Trends in prevalence of adverse childhood experiences by sociodemographic factors in the United States: Behavioral Risk Factor Surveillance System 2009-2022.BMC public health · 2024Article
- Association of adverse childhood experiences with anemia in older Chinese: Guangzhou Biobank Cohort Study.Scientific reports · 2024Article
- Serum osmolality was non-linearly associated with the risk of all-cause and cardiovascular mortality in patients with diabetes.BMJ open diabetes research & care · 2023Article
- Adverse childhood experiences are associated with vascular changes in adolescents that are risk factors for future cardiovascular disease.Pediatric nephrology (Berlin, Germany) · 2023Article
- Adverse childhood experiences and health risk behaviours among adolescents and young adults: evidence from India.BMC public health · 2023Article
- Can adverse childhood experiences predict chronic health conditions? Development of trauma-informed, explainable machine learning models.Frontiers in public health · 2023Article
- Does Gender Affirming Hormone Therapy Increase the Risk of Kidney Disease?Seminars in nephrology · 2022Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
introductionEvidence suggests that individuals with a history of adverse childhood experiences have higher odds of developing kidney disease than individuals with no adverse childhood experiences. However, no study has examined the influence of coexisting adverse childhood experiences and kidney disease on mortality risk. This study uses a longitudinal survey of adults to examine the influence of coexisting adverse childhood experiences and decreased renal function on all-cause mortality in a sample of U.S. adults.
methodsA total of 1,205 adults participating in the Midlife Development in the United States series between 1995 and 2014 were used for this analysis performed in 2019. A total of 6 types of adverse childhood experiences were available in the data set, which were combined to create a dichotomous variable with any adverse experience counted as yes. Decreased renal function was defined as an estimated glomerular filtration rate <60 milliliter/minute/1.73 m
resultsIn fully adjusted models, adverse childhood experiences and decreased renal function were associated with increased all-cause mortality relative to neither (hazard ratio=2.85, 95% CI=1.30, 6.25). Decreased renal function only and adverse childhood experiences only were not significantly associated with all-cause mortality (hazard ratio=1.14, 95% CI=0.64, 2.04 and hazard ratio=1.55, 95% CI=0.44, 5.41, respectively). When using decreased renal function as the reference group, coexisting adverse childhood experiences and decreased renal function was associated with a 64% increased risk of all-cause mortality, though this relationship was not statistically significant.
conclusionsCoexistence of adverse childhood experiences and decreased renal function is associated with higher all-cause mortality than seen in individuals with neither adverse childhood experiences nor decreased renal function and may be associated with higher all-cause mortality than seen in individuals with decreased renal function alone. Future research is needed to better understand this potential association.
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