Evidence map›Paper›PMID 32690025›Full record

ArticleBMC medical informatics and decision making2020

Validation of an EMR algorithm to measure the prevalence of ADHD in the Canadian Primary Care Sentinel Surveillance Network (CPCSSN).

Rachael Morkem, Kenneth Handelman, John A Queenan, Richard Birtwhistle, David Barber

Open access · goldAbstract read
In one paragraph

Article in BMC medical informatics and decision making, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rachael MorkemResearch Associate, Centre for Studies in Primary Care, Queen's University, Kingston, Ontario, Canada. rachael.morkem@dfm.queensu.ca.ORCID 0000-0001-7023-1742
Kenneth HandelmanPsychiatrist, Centre for Integrative Mental Health, Oakville, Ontario, Canada.
John A QueenanSenior Epidemiologist, Centre for Studies in Primary Care, Queen's University, Kingston, Ontario, Canada.
Richard BirtwhistleProfessor of Family Medicine and Public Health Sciences, Centre for Studies in Primary Care, Queen's University, Kingston, Ontario, Canada.
David BarberNetwork Director and Assistant Professor, Centre for Studies in Primary Care, Queen's University, Kingston, Ontario, Canada.
Queen's University · CA

Funding

Shire Pharma Canada ULC 6020024
6 · The paper itself

Abstract

backgroundBuilding and validating electronic algorithms to identify patients with specific disease profiles using health data is becoming increasingly important to disease surveillance and population health management. The aim of this study was to develop and validate an algorithm to find patients with ADHD diagnoses within primary care electronic medical records (EMR); and then use the algorithm to describe the epidemiology of ADHD from 2008 to 2015 in a Canadian Primary care sample.

methodsThis was a cross sectional time series that used data from the Canadian Primary Care Sentinel Surveillance Network (CPCSSN), a repository of primary care EMR data. A sample of electronic patient charts from one local clinic were manually reviewed to determine the positive predictive value (PPV) and negative predictive value (NPV) of an ADHD case-finding algorithm. In each study year a practice population was determined, and the algorithm was used to measure an observed prevalence of ADHD. The observed prevalence was adjusted for misclassification, as measured by the validity indices, to obtain an estimate of the true prevalence. Estimates were calculated by age group (4-17 year olds, 18 to 34 year olds, and 35 to 64 year olds) and gender, and compared over time.

resultsThe EMR algorithm had a PPV of 98.0% (95% CI [92.5, 99.5]) and an NPV of 95.0% (95% CI [92.9, 98.6]). After adjusting for misclassification, it was determined that the prevalence of patients with a clinical diagnosis of ADHD has risen in all age groups between 2008 and 2015, most notably in children and young adults (6.92, 95% CI [5.62, 8.39] to 8.57, 95% CI [7.32, 10.00]; 5.73, 95% CI [4.40, 7.23] to 7.33, 95% CI [6.04, 8.78], respectively). The well-established gender gap persisted in all age groups across time but was considerably smaller in older adults compared to children and young adults.

conclusionOverall, the ADHD case-finding algorithm was found to be a valid tool to assess the epidemiology of ADHD in Canadian primary care practice. The increased prevalence of ADHD between 2008 and 2015 may reflect an improvement in the recognition and treatment of this disorder within primary care.

Indexed as

Attention Deficit Disorder with HyperactivityElectronic Health RecordsAdolescentAdultAlgorithmsCanadaChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalencePrimary Health CareSentinel SurveillanceAlgorithmAttention deficit-hyperactivity disorderPrevalenceValidation

Identifiers

PMID32690025
PMCPMC7370518
OpenAlexW3043001822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.