Evidence map›Paper›PMID 32690002›Full record

ArticleBMC urology2020

Urinary tract infection is associated with hypokalemia: a case control study.

Ai-Ling Shen, Hsiu-Li Lin, Hsiu-Chen Lin, Yuan-Fu Tseng, Chien-Yeh Hsu, Che-Yi Chou

Open access · goldAbstract read
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Article in BMC urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ai-Ling ShenDepartment of Neurology, Sijhih Cathay General Hospital, No.2, Ln. 59, Jiancheng Rd., Sijhih Dist, New Taipei City, 221, Taiwan.
Hsiu-Li LinDepartment of Neurology, Sijhih Cathay General Hospital, No.2, Ln. 59, Jiancheng Rd., Sijhih Dist, New Taipei City, 221, Taiwan.
Hsiu-Chen LinDepartment of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, No. 252, Wu-Xing Street, Taipei, 110, Taiwan.
Yuan-Fu TsengDepartment of Neurology, Sijhih Cathay General Hospital, No.2, Ln. 59, Jiancheng Rd., Sijhih Dist, New Taipei City, 221, Taiwan.
Chien-Yeh HsuGraduate Institute of Biomedical Informatics, Taipei Medical University, No. 252, Wu-Xing Street, Taipei, 110, Taiwan.
Che-Yi ChouDivision of Nephrology, Asia University Hospital, NO 222, Fuxin Rd, Wufeng Dist, Taichung, 413, Taiwan. cychou.chou@gmail.com.ORCID http://orcid.org/0000-0003-4029-9097
Cathay General Hospital · TWTaipei Medical University Hospital · TWAsia University · TWNational Taipei University of Nursing and Health Science · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypokalemia is a common clinical problem. The association between urinary tract infection (UTI) and hypokalemia is not clear. Hypokalemia is common in patients with UTI in clinical observation. The aim of the study is to determine if UTI is associated with hypokalemia.

methodsPatients hospitalized with UTI and the control group were retrieved from the Longitudinal Health Insurance Database 2005. The control group was patients hospitalized with other reasons and were matched for the confoundings of UTI and hypokalemia. We analyze the risk of hypokalemia using logistic regression and calculate the odds ratio (OR) and 95% confidence interval (CI) of OR.

resultsWe analyzed 43,719 UTI patients and control patients. Hypokalemia was found in 4540 (10.4%) patients with UTI and 1842 (4.2%) control patients. The percentage of patients with hypokalemia was higher in UTI patients (chi-square, p < 0.001). UTI was associated with hypokalemia and the odds ratio (OR) was 2.27 [95% confidence interval (CI): 2.17-2.41]. Cerebrovascular accident, chronic obstructive pulmonary disease, hypertension, congestive heart failure, diarrhea, medications including thiazides, sulfonamides, xanthines, and laxatives were independently associated with hypokalemia. Recurrent UTI was associated with hypokalemia in UTI patients (OR: 1.13, 95% CI: 1.05-1.23, p < 0.001).

conclusionsUrinary tract infection is associated with hypokalemia among inpatients. The association is independent of patients' comorbidities and medications. Recurrent UTI is associated with increased hypokalemia in UTI patients.

Indexed as

AgedAged, 80 and overCase-Control StudiesFemaleHumansHypokalemiaMaleMiddle AgedRecurrenceUrinary Tract InfectionsComorbiditiesDiarrheaHypokalemiaRecurrent UTISulfonamidesThiazidesUTI

Identifiers

PMID32690002
PMCPMC7372809
OpenAlexW3043559841

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.