Evidence map›Paper›PMID 32689984›Full record

ArticleBMC complementary medicine and therapies2020

HPLC-DAD analysis of Hyssopus Cuspidatus Boriss extract and mensuration of its antioxygenation property.

Lu Zhao, Zhihong Ji, Keao Li, Bo Wang, Ya Zeng, Shuge Tian

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Cuspidatyl Ferulate, a Novel Phenolic Acid fromAntioxidants (Basel, Switzerland) · 2025
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  7. Chemical Composition ofAntibiotics (Basel, Switzerland) · 2023
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  8. The influence ofFrontiers in pharmacology · 2023
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  9. Exploration of the Molecular Mechanisms ofBioMed research international · 2022
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  10. Simultaneous Determination of the Five Constituents in Maiwei Dihuang Pills by the HPLC-DAD Method.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  11. Renal Protective Effects ofFrontiers in pharmacology · 2021
    Article
  12. Network Pharmacology-Based Analysis of the Underlying Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lu ZhaoCollege of Pharmacy, Xinjiang Medical University, Urumqi, 830011, Xinjiang, China.
Zhihong JiXinjiang Qimu Medical Research Institute, Urumqi, 830002, Xinjiang, China.
Keao LiXinjiang Qimu Medical Research Institute, Urumqi, 830002, Xinjiang, China.
Bo WangExperimental Animal Center, Xinjiang Medical University, Urumqi, 830011, Xinjiang, China.
Ya ZengCollege of TCM, Xinjiang Medical University, Urumqi, China.
Shuge TianCollege of TCM, Xinjiang Medical University, Urumqi, China. tianshuge@hotmail.com.ORCID http://orcid.org/0000-0002-9307-3668
Xinjiang Medical University · CN

Funding

High throughput detection technology based on group science and project service of primer synthesis JSHT20150601Study on the mechanism of action and industrialization project of Uyghur medicine Hanchuan Zupa granule in treating asthma KJJH2014007
6 · The paper itself

Abstract

backgroundHyssopus cuspidatus Boriss has been used as an important ethnomedicinal plant for long to eliminate phlegm, relieve cough and as well as having antibacterial, antioxygenation, and antitumor activities. In this study, the polyphenol contents, flavonoid contents, free radical scavenging assay and animal antioxygenation property assay of ethanol extract of H. cuspidatus were measured.

methodsThis study determined the total polyphenol and flavonoid contents in H. cuspidatus by UV-VIS. Caffeic, ferulic, and rosmarinic acids were measured using HPLC-DAD. Free radical scavenging assay of H. cuspidatus was studied by colorimetric method. Animal antioxygenation property assay of H. cuspidatus was studied with mice by biochemical assay kits.

resultsThe total polyphenol and flavonoid contents of H. cuspidatus in 2017, 2018, 2019 were determined and the contents of H. cuspidatus in 2019 was the highest. In addition, rosmarinic acid was the phenolic acid with the highest content in H. cuspidatus. Compared with those of DPPH free radical, hydroxyl free radical, and superoxide anion free radical, the scavenging ability of H. cuspidatus of ABTS free radical was stronger, the average IC

conclusionsThese results suggest that H. cuspidatus exerts an antioxygenation property, which can be attributed to the contents of total polyphenol and flavonoid. Given its strong antioxygenation property, H. cuspidatus can be used as a new natural antioxidant in food preservation and disease treatment.

Indexed as

AnimalsAntioxidantsCaffeic AcidsChinaChromatography, High Pressure LiquidCinnamatesCoumaric AcidsDepsidesFlavonoidsFree Radical ScavengersHyssopus PlantMaleMiceMolecular StructurePlant ExtractsPolyphenolsAntioxidantscaffeic acidCaffeic AcidsCinnamatesCoumaric AcidsDepsidesferulic acidFlavonoidsFree Radical ScavengersPlant ExtractsPolyphenolsRosmarinic AcidAntioxygenation propertyFree radical scavengingHPLC-DADHyssopus cuspidatus BorissTotal polyphenol and flavonoid

Identifiers

PMID32689984
PMCPMC7370466
OpenAlexW3043640827

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.