Evidence map›Paper›PMID 32688213›Full record

ReviewCurrent opinion in cell biology2020

Clathrin-independent endocytosis, retrograde trafficking, and cell polarity.

Massiullah Shafaq-Zadah, Estelle Dransart, Ludger Johannes

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Submicron-Sampling of Living Cells by Macrophages.bioRxiv : the preprint server for biology · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. CCSer2 gates dynein activity at the cell periphery.The Journal of cell biology · 2025
    Article
  17. Article
  18. Virus infection and vesicle trafficking.Frontiers in immunology · 2025
    Review
  19. Article
  20. CCSer2 gates dynein activity at the cell periphery.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Massiullah Shafaq-ZadahInstitut Curie, PSL Research University, Cellular and Chemical Biology Unit, INSERM U1143, CNRS UMR3666, 26 rue d'Ulm, 75248 Paris Cedex 05, France. Electronic address: massiullah.shafaq-zadah@curie.fr.
Estelle DransartInstitut Curie, PSL Research University, Cellular and Chemical Biology Unit, INSERM U1143, CNRS UMR3666, 26 rue d'Ulm, 75248 Paris Cedex 05, France.
Ludger JohannesInstitut Curie, PSL Research University, Cellular and Chemical Biology Unit, INSERM U1143, CNRS UMR3666, 26 rue d'Ulm, 75248 Paris Cedex 05, France. Electronic address: ludger.johannes@curie.fr.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several mechanisms allow for cargo internalization into cells within membrane-bound endocytic carriers. How these internalization processes couple to specific pathways of intracellular distribution remains poorly explored. Here, we review uptake reactions that are independent of the conventional clathrin machinery. We discuss how these link to retrograde trafficking from endosomes to the Golgi apparatus and exemplify biological situations in which the polarized secretion capacity of the Golgi apparatus allows for retrograde cargoes to be delivered to specialized areas of the plasma membrane, such as the leading edge of migratory cells or the immunological synapse of immune cells. We also address the evidence that allows to position apicobasal polarity of epithelial cells in this context. The underlying theme is thereby the functional coupling between specific types of endocytosis to intracellular retrograde trafficking for protein cargoes that need to be localized in a highly polarized and dynamic manner to plasmalemmal subdomains.

Indexed as

Cell PolarityEndocytosisClathrinEndosomesHumansModels, BiologicalProtein TransportClathrinEndocytosisGalectinGlycobiologyIntracellular traffickingPolarityRetrograde transportShiga toxin

Identifiers

PMID32688213
PMCPMC7588825
OpenAlexW3043578968

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.