Evidence map›Paper›PMID 32687625›Full record

ArticleTropical medicine & international health : TM & IH2020

Using ex-ante economic evaluation to inform research priorities in pesticide self-poisoning prevention: the case of a shop-based gatekeeper training programme in rural Sri Lanka.

Sabine Margarete Damerow, Manjula Weerasinghe, Lizell Bustamante Madsen, Kristian Schultz Hansen, Melissa Pearson, Michael Eddleston, Flemming Konradsen

Abstract read
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sabine Margarete DamerowSection of Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Manjula WeerasingheDepartment of Community Medicine, Faculty of Medicine & Allied Sciences, Rajarata University of Sri Lanka, Anuradhapura, Sri Lanka.
Lizell Bustamante MadsenSection of Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Kristian Schultz HansenSection for Health Services Research, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Melissa PearsonSouth Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Michael EddlestonSouth Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Flemming KonradsenSection of Global Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Funding

American Foundation for Suicide Prevention IIG-0-002-17University of Copenhagen
6 · The paper itself

Abstract

objectivesSuicide by pesticide self-poisoning is a major public health challenge in low- and middle-income countries. While effectiveness studies are required to test alternative prevention approaches, economic evidence is lacking to inform decision-making in research priority setting. Therefore, this study aimed to estimate the costs of a shop-based gatekeeper training programme for pesticide vendors seeking to prevent pesticide self-poisoning in rural Sri Lanka and assess its potential for cost-effectiveness.

methodsEx-ante cost and cost-effectiveness threshold (CET) analyses were performed from a governmental perspective based on a three-year analytic horizon, using 'no programme' as a comparator. A programme model targeting all 535 pesticide shops in the North Central Province and border areas was applied. Total programme costs (TPC) were estimated in 2019 USD using an ingredients approach and 3% annual discounting. The Sri Lankan gross domestic product per capita and life years saved were used as CET and effectiveness measure, respectively. Sensitivity analyses were performed.

resultsTPC were estimated at 31 603.03 USD. TPC were sensitive to cost changes of training material and equipment and the programme lifetime. The programme needs to prevent an estimated 0.23 fatal pesticide self-poisoning cases over three years to be considered cost-effective. In the sensitivity analyses, the highest number of fatal cases needed to be prevented to obtain cost-effectiveness was 4.55 over three years.

conclusionsFrom an economic perspective, the programme has a very high potential to be cost-effective. Research assessing its effectiveness should therefore be completed, and research analysing its transferability to other settings prioritised.

Indexed as

CommerceCost-Benefit AnalysisEducationGatekeepingHumansPesticidesRural PopulationSri LankaSuicide, AttemptedPesticidesanalyse du seuil de rentabilitéauto-intoxication aux pesticidescost-effectiveness threshold analysisétablissement des priorités de rechercheévaluation économique ex anteex-ante economic evaluationpesticide self-poisoningprévention du suicideresearch priority settingSri Lankasuicide prevention

Identifiers

PMID32687625
PMCPMC7589374

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.