ArticleACS chemical biology2020
Imaginary Ribozymes.
Article in ACS chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Structure and catalytic activity of the SAM-utilizing ribozyme SAMURI.Nature chemical biology · 2026Article
- The Role of General Acid Catalysis in the Mechanism of an Alkyl Transferase Ribozyme.ACS catalysis · 2024Article
- Full-Length NADBiochemistry · 2023Article
- Biological Catalysis and Information Storage Have Relied onBiomolecules · 2023Review
- Discovering riboswitches: the past and the future.Trends in biochemical sciences · 2023Review
- Identification and characterization of RNA binding sites for (p)ppGpp using RNA-DRaCALA.Nucleic acids research · 2023Article
- Review
- An RNA aptamer that shifts the reduction potential of metabolic cofactors.Nature chemical biology · 2022Article
- Structure and mechanism of the methyltransferase ribozyme MTR1.Nature chemical biology · 2022Article
- Structure and mechanism of a methyltransferase ribozyme.Nature chemical biology · 2022Article
- The Biochemical Landscape of Riboswitch Ligands.Biochemistry · 2022Article
- A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control.Nature communications · 2022Article
- Thermal adaptation of structural dynamics and regulatory function of adenine riboswitch.RNA biology · 2021Article
- The Baltimore Classification of Viruses 50 Years Later: How Does It Stand in the Light of Virus Evolution?Microbiology and molecular biology reviews : MMBR · 2021Review
- A natural riboswitch scaffold with self-methylation activity.Nature communications · 2021Article
- The case of the missing allosteric ribozymes.Nature chemical biology · 2021Review
- Synthesis ofBeilstein journal of organic chemistry · 2021Article
- An RNA-centric historical narrative around the Protein Data Bank.The Journal of biological chemistryReview
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Biocatalysis is dominated by protein enzymes, and only a few classes of ribozymes are known to contribute to the task of promoting biochemical transformations. The RNA World theory encompasses the notion that earlier forms of life made use of a much greater diversity of ribozymes and other functional RNAs to guide complex metabolic states long before proteins had emerged in evolution. In recent years, the discoveries of various classes of ribozymes, riboswitches, and other noncoding RNAs in bacteria have provided additional support for the hypothesis that RNA molecules indeed have the catalytic competence to promote diverse chemical reactions without the aid of protein enzymes. Herein, some of the most striking observations made from examinations of natural riboswitches that bind small ligands are highlighted and used as a basis to imagine the characteristics and functions of long-extinct ribozymes from the RNA World.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.