Evidence map›Paper›PMID 32687217›Full record

ArticleAmerican journal of industrial medicine2020

The effect of age on the relative risk of lung cancer mortality in a cohort of chromium production workers.

Herman Gibb, Jing Wang, Keri O'Leary, Chao Chen, Thomas F Bateson, Leonid Kopylev

Open access · hybridAbstract read
In one paragraph

Article in American journal of industrial medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Herman GibbGibb Epidemiology Consulting, Arlington, Virginia.ORCID 0000-0001-8537-1692
Jing WangGibb Epidemiology Consulting, Arlington, Virginia.
Keri O'LearyGibb Epidemiology Consulting, Arlington, Virginia.
Chao ChenGibb Epidemiology Consulting, Arlington, Virginia.
Thomas F BatesonChemical and Pollutant Assessment Division, Center for Public Health and Environmental Assessment, US Environmental Protection Agency, Washington, DC.
Leonid KopylevChemical and Pollutant Assessment Division, Center for Public Health and Environmental Assessment, US Environmental Protection Agency, Washington, DC.
OAI Consulting (United States) · USEnvironmental Protection Agency · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHexavalent chromium has been found to increase the risk of lung cancer in occupational studies. It has been suggested that the relative risk of lung cancer may vary by age.

methodsThe cohort examined is the Baltimore cohort of chromium production workers. The effect of age on the lung cancer risk from hexavalent chromium exposure was examined using a conditional Poisson regression modeling approach of Richardson and Langholz (R&L) and Cox models with interaction terms of age and cumulative hexavalent chromium exposure.

resultsThe inclusion of multiple age groups in the R&L approach suggests the existence of an age effect that is also supported by a Cox proportional hazard analysis. The hazard ratio in Cox models with age-cumulative exposure interaction terms was significantly elevated for the youngest age group and significantly decreased for the oldest age group.

conclusionsOur analyses are consistent with the observation that younger chromium production workers have a greater lung cancer risk than older workers.

Indexed as

Age FactorsAdolescentAdultAgedAir Pollutants, OccupationalBaltimoreChemical IndustryChromiumCohort StudiesFemaleHumansLung NeoplasmsMaleMiddle AgedOccupational DiseasesOccupational ExposureAir Pollutants, OccupationalChromiumchromium hexavalent ionchromium (VI)conditional Poisson regressionlung cancerproportional hazardRichardson Langholz

Identifiers

PMID32687217
PMCPMC7496708
OpenAlexW3044364468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.