Evidence map›Paper›PMID 32687041›Full record

ArticleEmerging infectious diseases2020

Presence of Segmented Flavivirus Infections in North America

Kurt J Vandegrift, Arvind Kumar, Himanshu Sharma, Satyapramod Murthy, Laura D Kramer, Richard Ostfeld, Peter J Hudson, Amit Kapoor

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

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  5. TITAN-RNA: A hybrid-capture sequencing panel detects known and unknownbioRxiv : the preprint server for biology · 2025
    Article
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  20. Discovery and Surveillance of Tick-Borne Pathogens.Journal of medical entomology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Kurt J Vandegrift
Arvind Kumar
Himanshu Sharma
Satyapramod Murthy
Laura D Kramer
Richard Ostfeld
Peter J Hudson
Amit Kapoor
Cary Institute of Ecosystem Studies · USPennsylvania State University · USCenter for Disease Dynamics, Economics & Policy · USNationwide Children's Hospital · USWadsworth Center · US

Funding

Host response and liver disease in a hepatitis C-like virus rat modelR01AI137567 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KAPOOR, AMIT · 2018 to 2022
$2.5M
Novel viruses and viral dynamics in multiple transfusion recipientsR01HL119485 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KAPOOR, AMIT · 2014 to 2018
$2.0M
Origin and evolution of virome in development of post-transfusion hepatitisR21HL140269 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KAPOOR, AMIT · 2017 to 2018
$228k
NHLBI NIH HHS R01 HL119485NHLBI NIH HHS R21 HL140269NIAID NIH HHS R01 AI137567
6 · The paper itself

Abstract

Identifying viruses in synanthropic animals is necessary for understanding the origin of many viruses that can infect humans and developing strategies to prevent new zoonotic infections. The white-footed mouse, Peromyscus leucopus, is one of the most abundant rodent species in the northeastern United States. We characterized the serum virome of 978 free-ranging P. leucopus mice caught in Pennsylvania. We identified many new viruses belonging to 26 different virus families. Among these viruses was a highly divergent segmented flavivirus whose genetic relatives were recently identified in ticks, mosquitoes, and vertebrates, including febrile humans. This novel flavi-like segmented virus was found in rodents and shares ≤70% aa identity with known viruses in the highly conserved region of the viral polymerase. Our data will enable researchers to develop molecular reagents to further characterize this virus and its relatives infecting other hosts and to curtail their spread, if necessary.

Indexed as

FlavivirusFlavivirus InfectionsAnimalsMiceNew EnglandNorth AmericaPennsylvaniaAlongshanarbovirusdeer mice viromeflavivirusesJingmen tick virusnortheastern United Statessynanthropic animalstick-borne virusesticksvectorborne infectionsviral metagenomicsviruseswhite-footed mousezoonoses

Identifiers

PMID32687041
PMCPMC7392405
OpenAlexW3038449543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.