ArticleScandinavian journal of primary health care2020
Different antibiotic regimes in men diagnosed with lower urinary tract infection - a retrospective register-based study.
Article in Scandinavian journal of primary health care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Safety of Fluoroquinolones and Cotrimoxazole in Urinary Tract Infections in Older Males.Open forum infectious diseases · 2026Article
- Testicular cancer incidence and associations with prior epididymo-orchitis or urinary tract infections: a national cohort study in Sweden, 1964-2018.BMJ oncology · 2026Article
- Bacterial growth and antimicrobial resistance in urinaryJAC-antimicrobial resistance · 2025Article
- Acute cystitis and subsequent risk of urogenital cancer: a national cohort study from Sweden.BMJ public health · 2025Article
- 'Male cystitis does not exist': A qualitative study of general practitioners' experiences and management of male urinary tract infections in France.The European journal of general practice · 2024Article
- Acute cystitis in men- a nationwide study from primary care: antibiotic prescriptions, risk factors, and complications.BJGP open · 2024Article
- Variation in Antibiotic Treatment Failure Outcome Definitions in Randomised Trials and Observational Studies of Antibiotic Prescribing Strategies: A Systematic Review and Narrative Synthesis.Antibiotics (Basel, Switzerland) · 2022Review
- Microbiology testing and antibiotic treatment for urinary tract infections in general practice: a nationwide observational study.Infection · 2021Observational
- What Left for Us for Urinary Tract Infection Treatment? An Experience from the South of Iran.Advanced biomedical research · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
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Abstract
objectiveTo compare the proportion of therapy failure, recurrence and complications within 30 days after consultation between men diagnosed with lower urinary tract infection (UTI) treated with narrow-spectrum antibiotics (nitrofurantoin or pivmecillinam) and broad-spectrum antibiotics (fluoroquinolones or trimethoprim or trimethoprim/sulfamethoxazole).
designA retrospective cohort study based on data derived from electronic medical records between January 2012 and December 2015.
settingPrimary health care and hospital care in five different counties in Sweden.
main outcome measuresTreatment with narrow-spectrum antibiotics was compared with broad-spectrum antibiotics regarding therapy failure, recurrence and complications within 30 days.
resultsThe median age of included men was 65 IQR (51-72) years. Narrow-spectrum antibiotics were prescribed in 8457 (40%) and broad-spectrum antibiotics in 12,667 (60%) cases, respectively. Therapy failure was registered in 192 (0.9%), recurrence in 1277 (6%) and complications in 121 (0.6%) cases. Therapy failure and recurrence were more common in patients treated with narrow-spectrum antibiotics and trimethoprim (
conclusionThere was no difference in incidence of complications within 30 days between men treated with narrow- or broad-spectrum antibiotics. Patients prescribed broad-spectrum antibiotics had lower odds of reconsultation because of therapy failure and recurrence. From current data, treatment with narrow-spectrum antibiotics seems to be an optimal choice regarding preventing complications when treating men with lower UTI. KEY POINTS Complications such as pyelonephritis and sepsis are uncommon in men diagnosed with lower urinary tract infection treated with antibiotics. There was no difference in incidence of complications among men diagnosed with lower urinary tract infection treated with narrow- or broad-spectrum antibiotics. In spite of higher incidence of therapy failure and recurrence, treatment with narrow-spectrum antibiotics seems to be an optimal choice regarding preventing complications when treating men diagnosed with lower UTI.
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