Evidence map›Paper›PMID 32686622›Full record

ArticleEmerging microbes & infections2020

Identification of a new strain of mouse kidney parvovirus associated with inclusion body nephropathy in immunocompromised laboratory mice.

Zhongming Ge, Sebastian E Carrasco, Yan Feng, Vasudevan Bakthavatchalu, Damodaran Annamalai, Robin Kramer, Sureshkumar Muthupalani, James G Fox

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Guidance on Establishing Health Monitoring Panels for Laboratory Mice to Reflect Contemporary Pathogen Prevalence.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Review
  2. Article
  3. European Hedgehogs as Hosts of Chaphamaparvovirus, Italy.Animals : an open access journal from MDPI · 2024
    Article
  4. Article
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  13. Serum IL-6 as a marker of disease progression in interstitial nephritis.American journal of translational research · 2022
    Article
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhongming GeDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Sebastian E CarrascoDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Yan FengDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Vasudevan BakthavatchaluDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Damodaran AnnamalaiDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Robin KramerDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Sureshkumar MuthupalaniDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
James G FoxDivision of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA.
Massachusetts Institute of Technology · US

Funding

TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LEVINE, STUART S · 1985 to 2020
$25.6M
NIEHS NIH HHS P30 ES002109
6 · The paper itself

Abstract

Inclusion body nephropathy (IBN) and kidney fibrosis in aged immunodeficient mice and, to lesser extent, in immunocompetent mice have been recently linked to infection of mouse kidney parvovirus (MKPV), also known as murine chapparvovirus (MuCPV). Knowledge about its prevalence and the complete genome sequence of more MKPV strains is essential for understanding phylogenetic relationships and pathogenicity among MKPV strains. In the present study using PCR and genome walking, we determined the complete 4440-nucleotide genome of a new MKPV strain, namely MIT-WI1, which was identified in IBN-affected

Indexed as

Amino Acid SequenceAnimalsFibrosisGenome, ViralImmunocompromised HostInclusion Bodies, ViralKidneyMiceMice, Inbred C57BLMice, Inbred ICRMice, Inbred NODMice, KnockoutNervous System DiseasesParvoviridae InfectionsParvovirusgenome organizationIBNMKPVPCR diagnosis

Identifiers

PMID32686622
PMCPMC7473309
OpenAlexW3042359720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.