Evidence map›Paper›PMID 32686373›Full record

ArticleJournal of Korean medical science2020

Acute Kidney Injury and Kidney Damage in COVID-19 Patients.

Ki Ryang Na, Hae Ri Kim, Youngrok Ham, Dae Eun Choi, Kang Wook Lee, Jae Young Moon, Yeon Sook Kim, Shinhye Cheon, Kyung Mok Sohn, Jungok Kim and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
0.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Mechanisms of SARS-CoV-2 Infection-Induced Kidney Injury: A Literature Review.Frontiers in cellular and infection microbiology · 2022
    Review
  12. Kidney injury in COVID-19 patients, drug development and their renal complications: Review study.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Ki Ryang NaDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-0136-176X
Hae Ri KimDepartment of Nephrology, Chungnam National University Sejong Hospital, Sejong, Korea.ORCID https://orcid.org/0000-0001-8766-6064
Youngrok HamDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0001-9140-6900
Dae Eun ChoiDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-2870-3958
Kang Wook LeeDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-3407-1205
Jae Young MoonDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0001-8724-6289
Yeon Sook KimDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-1142-5488
Shinhye CheonDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-1783-121X
Kyung Mok SohnDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-3237-044X
Jungok KimDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-0694-1579
Sungmin KimDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-3518-966X
Hyeongseok JeongDepartment of Infectious Disease, Chungnam National University Hospital, Daejeon, Korea.ORCID https://orcid.org/0000-0002-4539-079X
Jae Wan JeonDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0003-4256-3672
Chungnam National University · KRChungnam National University Hospital · KRSejong University · KR

Funding

National Research Foundation of Korea NRF-2018R1D1A1B07050193
6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This disease, which is quickly spreading worldwide, has high potential for infection and causes rapid progression of lung lesions, resulting in a high mortality rate. This study aimed to investigate the effects of SARS-CoV-2 infection on renal function in patients with COVID-19.

methodsFrom February 21 to April 24, 2020, 66 patients diagnosed with COVID-19 at Chungnam National University Hospital were analyzed; all patients underwent routine urinalysis and were tested for serum creatinine, urine protein to creatinine ratio (PCR), and urine albumin to creatinine ratio (ACR).

resultsAcute kidney injury (AKI) occurred in 3 (4.5%) of the 66 patients, and 1 patient with AKI stage 3 underwent hemodialysis. Upon follow-up, all 3 patients recovered normal renal function. Compared with patients with mild COVID-19, AKI (n = 3) occurred in patients with severe COVID-19, of whom both urine PCR and ACR were markedly increased.

conclusionThe incidence of AKI was not high in COVID-19 patients. The lower mortality rate in SARS-CoV-2 infection compared with previous Middle East respiratory syndrome and SARS-CoV infections is thought to be associated with a low incidence of dysfunction in organs other than the lungs.

Indexed as

Acute Kidney InjuryAgedAlbuminsAlbuminuriaBetacoronavirusCoronavirus InfectionsCOVID-19CreatinineFemaleGlomerular Filtration RateHumansKidney Function TestsMaleMiddle AgedPandemicsPneumonia, ViralAlbuminsCreatinineAcute Kidney InjuryCoronavirus Disease 2019COVID-19ProteinuriaSARS-CoV-2Severe Acute Respiratory Syndrome Coronavirus 2

Identifiers

PMID32686373
PMCPMC7371456
OpenAlexW3040897476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.