Evidence map›Paper›PMID 32686215›Full record

ArticleWound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society2020

Evolution of ischemia and neovascularization in a murine model of full thickness human wound healing.

Aos S Karim, Aiping Liu, Christie Lin, Adam J Uselmann, Kevin W Eliceiri, Matthew E Brown, Angela L F Gibson

Open access · greenAbstract read
In one paragraph

Article in Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Blank Spots in the Map of Human Skin: The Challenge for Xenotransplantation.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Robbing Peter to Pay Paul: Chlorhexidine gluconate demonstrates short-term efficacy and long-term cytotoxicity.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2022
    Article
  9. Xenograft Skin Model to Manipulate Human Immune Responses In Vivo.Journal of visualized experiments : JoVE · 2022
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Aos S KarimDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0003-2117-1805
Aiping LiuDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Christie LinOnLume Inc., Madison, Wisconsin, USA.
Adam J UselmannOnLume Inc., Madison, Wisconsin, USA.
Kevin W EliceiriOnLume Inc., Madison, Wisconsin, USA.ORCID 0000-0001-8678-670X
Matthew E BrownDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Angela L F GibsonDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0003-1181-7481
University of Wisconsin–Madison · US

Funding

Skin Diseases Research Center at the University of WisconsinP30AR066524 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI LONGLEY, B JACK · 2014 to 2018
$2.6M
Ergonomic fluorescence-guided surgery imaging platform for intraoperative assessment of blood and lymphatic vasculatureR44CA206754 · NCI · ONLUME, LLC · PI USELMANN, ADAM JOHN · 2020 to 2021
$1.9M
University of Wisconsin Transplant Reseach Training ProgramT32AI125231 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KAUFMAN, DIXON B · 2016 to 2020
$1.2M
Transient Lighting for Fluorescence Image-Guided SurgeryR43CA206754 · NCI · ONLUME, LLC · PI USELMANN, ADAM JOHN · 2016 to 2016
$300k
Genetic Engineering of Human Skin SubstitutesF31EB005437 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI GIBSON, ANGELA L F · 2005 to 2006
$61k
NCI NIH HHS R43 CA206754NCI NIH HHS R44 CA206754NIAID NIH HHS T32 AI125231NIAMS NIH HHS P30 AR066524NIBIB NIH HHS F31 EB005437
6 · The paper itself

Abstract

Translation of wound healing research is limited by the lack of an appropriate animal model, due to the anatomic and wound healing differences in animals and humans. Here, we characterize healing of grafted, full-thickness human skin in an in vivo model of wound healing. Full-thickness human skin, obtained from reconstructive operations, was grafted onto the dorsal flank of NOD.Cg-Kit

Indexed as

AngiographyAnimalsBurnsDisease Models, AnimalFemaleFlow CytometryHumansIschemiaMaleMiceMice, Inbred NODNeovascularization, PathologicSkinSkin TransplantationTransplantation, HeterologousWound Healing

Identifiers

PMID32686215
PMCPMC8592059
OpenAlexW3045216826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.