Evidence map›Paper›PMID 32686056›Full record

ReviewCurrent genetics2020

The past determines the future: sugar source history and transcriptional memory.

Poonam Bheda, Antonis Kirmizis, Robert Schneider

Open access · hybridAbstract readReview
In one paragraph

Review in Current genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Poonam BhedaInstitute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany. poonam.bheda@helmholtz-muenchen.de.ORCID http://orcid.org/0000-0001-6587-9456
Antonis KirmizisEpigenetics Lab, Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus.
Robert SchneiderInstitute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany.
Helmholtz Zentrum München · DEUniversity of Cyprus · CY

Funding

AMPro ZT0026Deutsche Forschungsgemeinschaft 213249687Deutsche Forschungsgemeinschaft 325871075European Regional Development Fund EXCELLENCE/0918/0105European Regional Development Fund EXCELLENCE/1216/0215
6 · The paper itself

Abstract

Transcriptional reinduction memory is a phenomenon whereby cells "remember" their transcriptional response to a previous stimulus such that subsequent encounters with the same stimulus can result in altered gene expression kinetics. Chromatin structure is thought to play a role in certain transcriptional memory mechanisms, leading to questions as to whether and how memory can be actively maintained and inherited to progeny through cell division. Here we summarize efforts towards dissecting chromatin-based transcriptional memory inheritance of GAL genes in Saccharomyces cerevisiae. We focus on methods and analyses of GAL (as well as MAL and INO) memory in single cells and discuss the challenges in unraveling the underlying mechanisms in yeast and higher eukaryotes.

Indexed as

Transcription, GeneticChromatinGalactokinaseGalactoseGene Expression Regulation, FungalSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSingle-Cell AnalysisSugarsChromatinGalactokinaseGalactoseSaccharomyces cerevisiae ProteinsSugarsChromatinGALHistory-dependent behaviorInheritanceMicrofluidicsSingle-cellTranscriptional memory

Identifiers

PMID32686056
PMCPMC7599190
OpenAlexW3043675670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.