Evidence map›Paper›PMID 32686021›Full record

ArticleMikrochimica acta2020

Designing a magnetic inductive micro-electrode for virus monitoring: modelling and feasibility for hepatitis B virus.

Elias Alipour, Seyed Peyman Shariatpanahi, Hedayatollah Ghourchian, Benoit Piro, Morteza Fathipour, Seyed Mehdi Boutorabi, Sergey L Znoyko, Petr I Nikitin

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elias AlipourInstitute of Biochemistry and Biophysics (IBB), University of Tehran, P. O. Box 13145-1384, Tehran, Iran.
Seyed Peyman ShariatpanahiInstitute of Biochemistry and Biophysics (IBB), University of Tehran, P. O. Box 13145-1384, Tehran, Iran.
Hedayatollah GhourchianInstitute of Biochemistry and Biophysics (IBB), University of Tehran, P. O. Box 13145-1384, Tehran, Iran. ghourchian@ut.ac.ir.ORCID http://orcid.org/0000-0003-0541-9209
Benoit PiroUniversité de Paris, ITODYS, CNRS, F-75006, Paris, France.
Morteza FathipourMEMS & NEMES Laboratory, Department of Electrical and Computer Engineering, University of Tehran, North kargar Ave., Tehran, Iran.
Seyed Mehdi BoutorabiPishtazteb Medical Co, Tehran, 1494734463, Iran.
Sergey L ZnoykoProkhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilov St, Moscow, Russia, 119991.
Petr I NikitinProkhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilov St, Moscow, Russia, 119991.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple model is designed for an inductive immunosensor in which the magnetic particles are attached to the bioreceptors to form a sandwich on the surface of an inductor. The inductor consists of a coil covered on a silicon oxide wafer. The coil comprises 250 turns of a planar gold wire, which is approximately 200 nm thick and 392 mm long, placed in a circle with a diameter of 2 mm. The model is well characterised by controlling the geometrical and electrical parameters and also the permeability of the magnetic material. To evaluate the feasibility of the model for virus monitoring, a novel inductive immunosensor is designed and for the first time applied for the detection of hepatitis B surface antigen (HBsAg). At first, Fab' segment of primary anti-HBsAg is immobilised on the coil. Then, the coil is exposed to HBsAg and the complex is introduced to a secondary antibody conjugated with magnetic particles to form an immune-sandwich. Finally, the influence of magnetic particles on the coil inductance is recorded and used as a signal for HBsAg detection. The magnetic inductive immunosensor showed specific responses toward HBsAg with the detection limit of 1 ng mL

Indexed as

AnimalsAntibodies, ImmobilizedAntibodies, MonoclonalBiosensing TechniquesHepatitis B Surface AntigensHepatitis B virusHumansImmunoassayImmunoglobulin Fab FragmentsLimit of DetectionMagnetic PhenomenaMetal NanoparticlesMiceMicroelectrodesAntibodies, ImmobilizedAntibodies, MonoclonalHepatitis B Surface AntigensImmunoglobulin Fab FragmentsHepatitis B surface antigenInductive immunosensorMagnetic nanoparticlesSpiral inductorVirus monitoring

Identifiers

PMID32686021

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.