Evidence map›Paper›PMID 32685922›Full record

ArticlePlant communications2020

Over 100 Million Years of Enzyme Evolution Underpinning the Production of Morphine in the Papaveraceae Family of Flowering Plants.

Yi Li, Thilo Winzer, Zhesi He, Ian A Graham

Open access · goldAbstract read
In one paragraph

Article in Plant communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. The origins and spread of the opium poppy (Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
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  12. Current topics in medicinal chemistry · 2024
    Review
  13. Divergent proteomic profiles of opium poppy cultivars.Turkish journal of biology = Turk biyoloji dergisi · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. California poppy (Frontiers in plant science · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yi LiCentre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5YW, UK.
Thilo WinzerCentre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5YW, UK.
Zhesi HeCentre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5YW, UK.
Ian A GrahamCentre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5YW, UK.
University of York · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phylogenomic analysis of whole genome sequences of five benzylisoquinoline alkaloid (BIA)-producing species from the Ranunculales and Proteales orders of flowering plants revealed the sequence and timing of evolutionary events leading to the diversification of these compounds. (

Indexed as

Evolution, MolecularBenzophenanthridinesBenzylisoquinolinesBerberine AlkaloidsEnzymesGene DuplicationIsoquinolinesMorphinansMorphineMultigene FamilyNoscapinePapaveraceaePhylogenyPlant ProteinsBenzophenanthridinesBenzylisoquinolinesBerberine AlkaloidsEnzymesIsoquinolinesMorphinansMorphineNoscapinePlant Proteinsprotoberberinereticulinesanguinarinebenzylisoquinoline alkaloidsgene clustersgene fusiongene tree analysismetabolic pathway evolutionplant genomes

Identifiers

PMID32685922
PMCPMC7357826
OpenAlexW3004541395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.