Evidence map›Paper›PMID 32685904›Full record

ArticleResearch and practice in thrombosis and haemostasis2020

The odds and implications of coinheritance of hemophilia A and B.

Corinne Karch, Diane Masser-Frye, Jacqueline Limjoco, Sarah E Ryan, Shelley N Fletcher, Kevin D Corbett, Jill M Johnsen, Courtney D Thornburg

Open access · goldAbstract readCase Reports
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. The odds and implications of coinheritance of hemophilia A and B.Research and practice in thrombosis and haemostasis · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Corinne KarchVirginia Commonwealth University School of Medicine Richmond Virginia USA.
Diane Masser-FryeRady Children's Hospital San Diego San Diego California USA.
Jacqueline LimjocoRady Children's Hospital San Diego San Diego California USA.
Sarah E RyanBloodworks Northwest Seattle Washington USA.
Shelley N FletcherBloodworks Northwest Seattle Washington USA.
Kevin D CorbettDepartment of Cellular and Molecular Medicine University of California San Diego La Jolla California USA.ORCID https://orcid.org/0000-0001-5854-2388
Jill M JohnsenBloodworks Northwest Seattle Washington USA.ORCID https://orcid.org/0000-0002-2279-2550
Courtney D ThornburgRady Children's Hospital San Diego San Diego California USA.ORCID https://orcid.org/0000-0002-5665-8958
Bloodworks Northwest · USRady Children's Hospital-San Diego · USUniversity of California San Diego · USUniversity of Washington · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report 2 patients with coinheritance of the X-linked bleeding disorders hemophilia A and hemophilia B. We describe the family pedigrees, clinical features, and genotyping. The case report addresses the key clinical questions of how to manage patients with both hemophilia A and B and how to counsel families regarding recurrence risk. The patients with coinherited hemophilia A and B require a combination of factor VIII and factor IX replacement to achieve hemostasis. We calculated the estimated genomic meiotic recombination frequency between

Indexed as

factor IXfactor VIIIgenetic counselinghemophiliapedigreerecombination genetic

Identifiers

PMID32685904
PMCPMC7354394
OpenAlexW3041397684

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.