Evidence map›Paper›PMID 32685876›Full record

ArticleResearch and practice in thrombosis and haemostasis2020

Illustrated State-of-the-Art Capsules of the ISTH 2020 Congress.

Robert Ariens, Cecilia Becattini, Markus Bender, Wolfgang Bergmeier, Elisabetta Castoldi, Katrien Devreese, Martin Ellis, David Gailani, Vera Ignjatovic, Paula D James and 19 more

Open access · goldAbstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 20 institutions in 14 countries.

Robert AriensDiscovery and Translational Science Department Leeds Institute of Cardiovascular and Metabolic Medicine University of Leeds Leeds UK.
Cecilia BecattiniInternal and Cardiovascular Medicine - Stroke Unit University of Perugia Perugia Italy.
Markus BenderInstitute of Experimental Biomedicine - Chair I University Hospital and Rudolf Virchow Center Würzburg Germany.
Wolfgang BergmeierDepartment of Biochemistry and Biophysics UNC Blood Research Center University of North Carolina at Chapel Hill Chapel Hill NC USA.
Elisabetta CastoldiCardiovascular Research Institute Maastricht (CARIM) Maastricht University Maastricht The Netherlands.
Katrien DevreeseCoagulation Laboratory Department of Laboratory Medicine Ghent University Hospital Ghent University Ghent Belgium.
Martin EllisHematology Institute and Blood Bank Meir Medical Center and Sackler School of Medicine Tel Aviv University Tel Aviv Israel.
David GailaniDepartment of Pathology, Microbiology and Immunology Vanderbilt University Medical Center Nashville TN USA.
Vera IgnjatovicHaematology Research Team Murdoch Children's Research Institute Department of Paediatrics The University of Melbourne Parkville Vic. Australia.
Paula D JamesQueen's University Kingston ON Canada.
Steven KerriganRoyal College of Surgeons in Ireland School of Pharmacy and Biomolecular Sciences Irish Centre for Vascular Biology Dublin Ireland.
Michele LambertDepartment of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia PA USA.
Lai Heng LeeDepartment of Haematology Singapore General Hospital SingHealth Singapore City Singapore.
Marcel LeviUniversity College London Hospitals London UK.
Norma MaugeriSan Raffaele Scientific Institute and Vita-Salute San Raffaele University Milano Italy.
Joost MeijersDepartment of Experimental Vascular Medicine Amsterdam University Medical Centers University of Amsterdam Amsterdam The Netherlands.
Juan Melero-MartinBoston Children's Hospital and Harvard Medical School Boston MA USA.
Alan D MichelsonBoston Children's Hospital and Harvard Medical School Boston MA USA.
Federico MingozziSpark Therapeutics Philadelphia PA USA.
Keith NeevesDepartment of Chemical and Biological Engineering Colorado School of Mines Golden CO USA.
Heyu NiDepartment of Laboratory Medicine and Keenan Research Centre for Biomedical Science of St. Michael's Hospital University of Toronto Toronto ON Canada.
Anna-Karin OlssonDepartment of Medical Biochemistry and Microbiology Uppsala University Uppsala Sweden.
Zoltán ProhászkaResearch Laboratory 3rd Department of Internal Medicine MTA-SE Research Group of Immunology and Hematology Hungarian Academy of Sciences and Semmelweis University Budapest Hungary.
Marie RansonSchool of Chemistry and Molecular Bioscience University of Wollongong Wollongong NSW Australia.
Nicoletta RivaDepartment of Pathology Faculty of Medicine and Surgery University of Malta Msida Malta.
Yotis SenisDirecteur de Recherche Etablissement Français du Sang Grand Est Inserm UMR-S1255 Université de Strasbourg Strasbourg France.
Cornelia H van OmmenDepartment of Pediatric Hematology Oncology Erasmus MC Sophia Children's Hospital Rotterdam The Netherlands.
Douglas E VaughanNorthwestern University Feinberg School of Medicine Chicago IL USA.
John WeiselDepartment of Cell and Developmental Biology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA.
University of Pennsylvania · USBoston Children's Hospital · USColorado School of Mines · USErasmus MC - Sophia Children’s Hospital · NLGhent University Hospital · BEHarvard University · USInserm · FRMaastricht University · NLMurdoch Children's Research Institute · AUNorthwestern University · USQueen's University · CARoyal College of Surgeons in Ireland · IESanquin · NLSemmelweis University · HUSingapore General Hospital · SGSpark Therapeutics (United States) · USSt. Michael's Hospital · CATel Aviv University · ILUniversity College London · GBUniversity of Leeds · GB

Funding

Characterization of Coagulation Factor-platelet Interactions: Role of FXIR01HL101972 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Owen J McCarty · 2010 to 2026
$8.5M
Contact Pathway Activation on Vascular DevicesR01HL144113 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HINDS, MONICA T, MCCARTY, OWEN J · 2018 to 2025
$6.0M
Biochemistry and Pathophysiology of Factor XI and Contact ActivationR35HL140025 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GAILANI, DAVID · 2018 to 2024
$5.5M
Vascular networks genetically engineered for protein drug deliveryR01HL128452 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI MELERO-MARTIN, JUAN M, WANG, BO · 2015 to 2024
$4.8M
British Heart Foundation PG/16/60/32292British Heart Foundation RG/13/3/30104British Heart Foundation RG/18/11/34036NHLBI NIH HHS R01 HL128452NHLBI NIH HHS R01 HL144113NHLBI NIH HHS R35 HL140025
6 · The paper itself

Abstract

The 2020 Congress of the International Society of Thrombosis and Haemostasis (ISTH) was held virtually July 12-15, 2019, due to the coronavirus disease 2019 pandemic. The congress convenes annually to discuss clinical and basic topics in hemostasis and thrombosis. Each year, the program includes State of Art (SOA) lectures given by prominent scientists. Presenters are asked to create Illustrated Capsules of their talks, which are concise illustrations with minimal explanatory text. Capsules cover major themes of the presentation, and these undergo formal peer review for inclusion in this article. Owing to the shift to a virtual congress this year, organizers reduced the program size. There were 39 SOA lectures virtually presented, and 29 capsules (9 from talks omitted from the virtual congress) were both submitted and successful in peer review, and are included in this article. Topics include the roles of the hemostatic system in inflammation, infection, immunity, and cancer, platelet function and signaling, platelet function disorders, megakaryocyte biology, hemophilia including gene therapy, phenotype tests in hemostasis, von Willebrand factor, anticoagulant factor V, computational driven discovery, endothelium, clinical and basic aspects of thrombotic microangiopathies, fibrinolysis and thrombolysis, antithrombotics in pediatrics, direct oral anticoagulant management, and thrombosis and hemostasis in pregnancy. Capsule authors invite virtual congress attendees to refer to these capsules during the live presentations and participate on Twitter in discussion.

Identifiers

PMID32685876
PMCPMC7354406
OpenAlexW3041261145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.