Evidence map›Paper›PMID 32685802›Full record

ArticleACS omega2020

A Novel Cyclic Mobile Transporter Can Induce Apoptosis by Facilitating Chloride Anion Transport into Cells.

Goutam Kulsi, Achinta Sannigrahi, Snehasis Mishra, Krishna Das Saha, Sriparna Datta, Partha Chattopadhyay, Krishnananda Chattopadhyay

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Recent Advances in Bioactive Artificial Ionophores.Chembiochem : a European journal of chemical biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Goutam KulsiStructural Biology and Bioinformatics Division, CSIR- Indian Institute of Chemical Biology (IICB), Kolkata 700032, India.
Achinta SannigrahiStructural Biology and Bioinformatics Division, CSIR- Indian Institute of Chemical Biology (IICB), Kolkata 700032, India.
Snehasis MishraCancer Biology and Inflammatory Disorder Division, CSIR- Indian Institute of Chemical Biology (IICB), Kolkata 700032, India.
Krishna Das SahaCancer Biology and Inflammatory Disorder Division, CSIR- Indian Institute of Chemical Biology (IICB), Kolkata 700032, India.
Sriparna DattaDepartment of Chemical Technology, University of Calcutta, Kolkata 700009, India.
Partha ChattopadhyayOrganic and Medicinal Chemistry Division, CSIR- Indian Institute of Chemical Biology (IICB), Kolkata 700032, India.
Krishnananda ChattopadhyayStructural Biology and Bioinformatics Division, CSIR- Indian Institute of Chemical Biology (IICB), Kolkata 700032, India.
Indian Institute of Chemical Biology · INUniversity of Calcutta · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here the preparation of an aminoxy amide-based pseudopeptide-derived building block using furanoid sugar molecules. Through the cyclo-oligomerization reaction, we generate a hybrid triazole/aminoxy amide macrocycle using the as-prepared building block. The novel conformation of the macrocycle has been characterized using NMR and molecular modeling studies, which show a strong resemblance of our synthesized compound to d-,l-α-aminoxy acid-based cyclic peptides that contain uniform backbone chirality. We observe that the macrocycle can efficiently and selectively bind Cl

Identifiers

PMID32685802
PMCPMC7364434
OpenAlexW3039682012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.