Evidence map›Paper›PMID 32685790›Full record

ArticleRomanian journal of ophthalmology

CRMP-5-IgG Antibody: role in the bilateral uveitis with swollen disc.

Laura Hernández-Bel, Francisco Puchades-Gimeno, Amaya Fernandez-Diaz, Lucía Mata-Moret, Emma Beltrán-Catalán, María Luísa Hernandez-Garfella, Enrique Cervera-Taulet

Open access · greenAbstract readCase Reports
PubMed Full text at PMC
In one paragraph

Article in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Laura Hernández-BelHospital General Valencia, València, Spain.
Francisco Puchades-GimenoHospital General Valencia, València, Spain.
Amaya Fernandez-DiazHospital General Valencia, València, Spain.
Lucía Mata-MoretHospital General Valencia, València, Spain.
Emma Beltrán-CatalánHospital del Mar, Barcelona, Spain.
María Luísa Hernandez-GarfellaHospital General Valencia, València, Spain.
Enrique Cervera-TauletHospital del Mar, Barcelona, Spain.
Hospital Del Mar · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmunity against collapsin response-mediator protein-5 (anti-CRMP-5) has been associated with ocular inflammation in paraneoplastic syndrome. We present a 59-year-old Caucasian man with optic neuritis and vitreous cells in both eyes (OU), at different stages. Despite the fact that the patient did not have any systemic disease, we suspected a paraneoplastic syndrome and requested CRMP-5-IgG and a mediastinoscopy. After performing the tests, a small cell lung carcinoma was diagnosed. Autoantibody CRMP-5-IgG positivity and optic neuritis combined with vitreous inflammation was defined as a paraneoplastic entity, avoiding vitreous biopsy and allowing us to suspect malignancy before systemic symptoms appeared.

Indexed as

AutoantibodiesFluorescein AngiographyFundus OculiHumansHydrolasesImmunoglobulin GMaleMicrotubule-Associated ProteinsMiddle AgedPapilledemaUveitisVisual FieldsAutoantibodiesDPYSL5 protein, humanHydrolasesImmunoglobulin GMicrotubule-Associated ProteinsCRMP-5 IgGoptic neuritisparaneoplastic conditionssmall cell lung carcinoma

Identifiers

PMID32685790
PMCPMC7339702
OpenAlexW3040319944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.