ArticleContemporary clinical trials communications2020
Site engagement for multi-site clinical trials.
Article in Contemporary clinical trials communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Mechanisms to expedite pediatric clinical trial site activation: The DOSE trial experience.Contemporary clinical trials · 2023Trial
- Evolving roles of Data Coordinating Centers in multisite research: Challenges and adaptations from a rapid scoping review.Journal of clinical and translational science · 2026Review
- Site engagement in implementation research: Introducing SEAMLIS as a conceptual and measurement framework.Health & justice · 2025Article
- Article
- Achieving Inclusion in Pharmacological Clinical Trials for Alzheimer's Disease.Current topics in behavioral neurosciences · 2025Review
- Enhancing Emergency Department Management: A Data-Driven Approach to Detect and Predict Surge Persistence.Healthcare (Basel, Switzerland) · 2024Article
- Using virtual multiteam systems to conduct a multisite randomized clinical trial in the part C early intervention system: Benefits, challenges, and lessons learned.Contemporary clinical trials · 2024Article
- An open natural language processing (NLP) framework for EHR-based clinical research: a case demonstration using the National COVID Cohort Collaborative (N3C).Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Promoting community stakeholder engagement in research on treatment for pregnant women with opioid use disorder.Journal of comparative effectiveness research · 2022Article
- Leveraging electronic health record data for clinical trial planning by assessing eligibility criteria's impact on patient count and safety.Journal of biomedical informatics · 2022Article
- Using gamification to enhance clinical trial start-up activities.Journal of clinical and translational science · 2022Article
- Making large-scale surgical trials possible: collaboration and the role of surgical trainees.Trials · 2021Article
- Recruiting underrepresented individuals in a double pandemic: Lessons learned in a randomized control trial.Journal of clinical and translational science · 2021Article
- Are we being equitable enough? Lessons learned from sites lost in an implementation trial.Implementation research and practiceArticle
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multi-site clinical trials are essential within medical practice to help drive reliable and generalizable knowledge on advancing medical treatments. Although the success of multi-site trials is significantly dependent on local clinician and site research teams, best practices for engagement of site teams, or "site engagement," has not been extensively discussed. Site engagement centers on including sites in the planning and implementation of clinical trials to promote trial enrollment, compliance, and applicability to local contexts. Using a case example from the RadComp Trial, a longitudinal, multi-site clinical trial, novel site engagement practices are provided across three major research phases. In the Planning Phase, site engagement builds partnerships and commitment by active elicitation of information on site specific processes and feedback on trial design. In the Conducting Phase, sustained engagement encourages bi-directional communication and facilitates learning networks for enhanced site performance. In the Dissemination Phase, site and community partnerships are leveraged to create locally designed dissemination plans for broader scientific reach and impact. Site engagement practices discussed in this paper can be replicated or molded for application in other multi-site clinical trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.