Evidence map›Paper›PMID 32685596›Full record

ArticleJournal of health economics and outcomes research2020

Machine Learning for Precision Health Economics and Outcomes Research (P-HEOR): Conceptual Review of Applications and Next Steps.

Yixi Chen, Viktor V Chirikov, Xiaocong L Marston, Jingang Yang, Haibo Qiu, Jianfeng Xie, Ning Sun, Chengming Gu, Peng Dong, Xin Gao

Abstract read
In one paragraph

Article in Journal of health economics and outcomes research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yixi ChenPfizer Investment Co. Ltd., Beijing, China.
Viktor V ChirikovReal World Evidence, Pharmerit International, Bethesda, Maryland, United States.
Xiaocong L MarstonReal World Evidence, Pharmerit International, Bethesda, Maryland, United States.
Jingang YangFuwai Hospital, Beijing, China.
Haibo QiuZhongda Hospital, Southeast University, Nanjing, China.
Jianfeng XieZhongda Hospital, Southeast University, Nanjing, China.
Ning SunEasy Visible Sky Tree Technology (Beijing) Co., Ltd., Beijing, China.
Chengming GuSanofi (China) Investment Co. Ltd., Beijing, China.
Peng DongPfizer Investment Co. Ltd., Beijing, China.
Xin GaoReal World Evidence, Pharmerit International, Bethesda, Maryland, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision health economics and outcomes research (P-HEOR) integrates economic and clinical value assessment by explicitly discovering distinct clinical and health care utilization phenotypes among patients. Through a conceptualized example, the objective of this review is to highlight the capabilities and limitations of machine learning (ML) applications to P-HEOR and to contextualize the potential opportunities and challenges for the wide adoption of ML for health economics. We outline a P-HEOR conceptual framework extending the ML methodology to comparatively assess the economic value of treatment regimens. Latest methodology developments on bias and confounding control in ML applications to precision medicine are also summarized.

Indexed as

cost-effectivenessnet monetary benefitpatient heterogeneityrandom forest

Identifiers

PMID32685596
PMCPMC7299485

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.