ArticleJournal of diabetes research2020
The Relationship between Perirenal Fat Thickness and Reduced Glomerular Filtration Rate in Patients with Type 2 Diabetes.
Article in Journal of diabetes research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Stage-specific utility of obesity indices across the chronic kidney disease continuum.Renal failure · 2026Article
- Perinephric fat volume and its negative correlation with the eGFR according to a population health screening: a cross-sectional study.Renal failure · 2025Article
- A framework of biomarkers for adipose tissue aging: a consensus statement by the Aging Biomarker Consortium.Life medicine · 2025Article
- A cross-sectional and bioinformatics-based analysis: perirenal fat thickness as a superior predictor of kidney stone disease.Lipids in health and disease · 2025Article
- Opportunistic Detection of Chronic Kidney Disease Using CT-Based Measurements of Kidney Volume and Perirenal Fat.Journal of clinical medicine · 2025Article
- The Role of Perirenal Adipose Tissue in Carcinogenesis-From Molecular Mechanism to Therapeutic Perspectives.Cancers · 2025Review
- The ratio of perirenal fat thickness to renal parenchymal thickness, a novel indicator of fat accumulation associated with kidney stones.Lipids in health and disease · 2025Article
- Anatomy, Histology, and Embryonic Origin of Adipose Tissue: Insights to Understand Adipose Tissue Homofunctionality in Regeneration and Therapies.Advances in experimental medicine and biology · 2025Review
- Emerging insights into the role of visceral adipose tissue in diabetic kidney disease.Frontiers in nutrition · 2025Review
- Correlations between biological markers of the perirenal adipose tissue and clinical features of patients with localized kidney cancer.Frontiers in medicine · 2025Article
- Preliminary quantitative analysis of renal sinus fat dysfunction in T2DM patients using MRI fat fraction and R2* mapping.Frontiers in endocrinology · 2025Article
- Relationships of Thickness of Perirenal Fat with Urinary Levels of MCP-1 and NGAL in Patients with Hypertension.Journal of obesity & metabolic syndrome · 2024Article
- Renal fat deposition measured on dixon-based MRI is significantly associated with early kidney damage in obesity.Abdominal radiology (New York) · 2024Article
- Abdominal adipose tissue and type 2 diabetic kidney disease: adipose radiology assessment, impact, and mechanisms.Abdominal radiology (New York) · 2024Review
- Thickened Perirenal Fat Predicts Poor Renal Outcome in Patients with Immunoglobulin A Nephropathy: A Population-Based Retrospective Cohort Study.Kidney diseases (Basel, Switzerland) · 2024Article
- Perirenal Fat Thickness Is Associated With Contrast-Induced Nephropathy in Type 2 Diabetic Patients Undergoing Coronary Catheterization.Journal of diabetes research · 2024Article
- High perirenal fat thickness predicts a greater risk of recurrence in Chinese patients with unilateral nephrolithiasis.Renal failure · 2023Article
- Upregulation in Inflammation and Collagen Expression in Perirenal but Not in Mesenteric Adipose Tissue from Diabetic Munich Wistar Frömter Rats.International journal of molecular sciences · 2023Article
- Article
- Perirenal Fat Thickness is Associated with Metabolic Dysfunction-Associated Fatty Liver Disease in Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
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6 authors.
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Abstract
backgroundObesity has been considered as an important factor in the development and progression of chronic kidney diseases (CKD). Perirenal fat, which is surrounding the kidneys, has been reported to be unique in anatomy and biological functions. This study is aimed at assessing the relationship between perirenal fat thickness (PrFT) and estimated glomerular filtration rate (eGFR) in patients with type 2 diabetes (T2DM).
methodsA total of 171 patients with T2DM were recruited in the study. The basic and clinical characteristics including sex, age, diabetes duration, body mass index (BMI), waist circumference (WC), visceral fat area (VFA), glycated hemoglobin (HbA1c), serum uric acid (UA), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), and high-density lipoprotein cholesterol (HDL-c) were collected. PrFT was measured via ultrasound. eGFR was calculated using the Modification of Diet in Renal Disease (MDRD) formula.
resultsPatients were divided into three groups according to PrFT, and we found patients with higher PrFT had lower eGFR. PrFT was significantly correlated with eGFR in all patients (
conclusionsThis study confirmed a negative independent relationship between PrFT and eGFR in patients with T2DM, especially in men, suggesting a possible role of perirenal fat in kidney dysfunction in T2DM patients.
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