Evidence map›Paper›PMID 32685543›Full record

SynthesisBioMed research international2020

Prevalence and Associated Factor of Brown Adipose Tissue: Systematic Review and Meta-Analysis.

Misganaw Gebrie Worku, Wullo Sisay Seretew, Dessie Abebaw Angaw, Getayeneh Antehunegn Tesema

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Brown Adipose Tissue and Its Role in Insulin and Glucose Homeostasis.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Misganaw Gebrie WorkuDepartment of Human Anatomy, University of Gondar, College of Medicine and Health Science, School of Medicine, Gondar, Ethiopia.ORCID https://orcid.org/0000-0002-7647-6449
Wullo Sisay SeretewDepartment of Epidemiology and Biostatistics, University of Gondar, College of Medicine and Health Science, Institute of Public Health, Gondar, Ethiopia.
Dessie Abebaw AngawDepartment of Epidemiology and Biostatistics, University of Gondar, College of Medicine and Health Science, Institute of Public Health, Gondar, Ethiopia.ORCID https://orcid.org/0000-0001-9827-2255
Getayeneh Antehunegn TesemaDepartment of Epidemiology and Biostatistics, University of Gondar, College of Medicine and Health Science, Institute of Public Health, Gondar, Ethiopia.ORCID https://orcid.org/0000-0001-6812-1659
University of Gondar · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrown adipose tissue generates heat instead of storing energy. It is important in the regulation of body weight, and individual variation in adaptive thermogenesis can be attributed to variations in the amount or activity of BAT.

objectiveThe objective of this study was to systematically review different articles to assess the prevalence of BAT and its associated factors and relation with obesity and diabetes mellitus.

methodsA systematic review and meta-analysis were employed on published research works from different electronic databases using keywords. Cross-sectional studies and a few experimental studies were included for systematic review, and only studies done on human population were used for quantitative analysis. Twenty-two peer-reviewed papers were included in the systematic review, and eight papers were used for the meta-analysis for estimation of pooled prevalence of brown adipose tissue using selection criteria.

resultsThe pooled prevalence of brown adipose tissue among adults was 6.97% (95% CI: 6.51-7.43), and it was 7.4% (95% CI 6.51-7.43) after sequential omission of a single study. The heterogeneity in estimating the pooled prevalence among the studies was statistically significant (Cochran

conclusionThe percentage of adult individuals with brown adipose tissue was high, and its activity was reduced in obese individuals. Although it is reduced in amount, still it presents in obese individuals. So, activation of the brown adipose tissue in adult and older individuals should be a target for the treatment of obesity.

Indexed as

ThermogenesisAdipose Tissue, BrownAdultHumansObesity

Identifiers

PMID32685543
PMCPMC7317326
OpenAlexW3034380584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.