Evidence map›Paper›PMID 32685480›Full record

ReviewBioMed research international2020

Current Progression: Application of High-Throughput Sequencing Technique in Space Microbiology.

Yanwu Chen, Bin Wu, Cheng Zhang, Zhiqi Fan, Ying Chen, Bingmu Xin, Qiong Xie

Abstract readReview
In one paragraph

Review in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Four Decades ofMicroorganisms · 2025
    Article
  3. From DNA to Big Data: NGS Technologies and Their Applications.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  4. Diversity of Endophytes ofLife (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanwu ChenSpace Science and Technology Institute (Shenzhen), Shenzhen, China.
Bin WuChina Astronaut Research and Training Center, Beijing, China.ORCID https://orcid.org/0000-0003-1430-4382
Cheng ZhangSpace Science and Technology Institute (Shenzhen), Shenzhen, China.
Zhiqi FanSpace Science and Technology Institute (Shenzhen), Shenzhen, China.
Ying ChenSpace Science and Technology Institute (Shenzhen), Shenzhen, China.
Bingmu XinSpace Science and Technology Institute (Shenzhen), Shenzhen, China.ORCID https://orcid.org/0000-0002-6421-6180
Qiong XieChina Astronaut Research and Training Center, Beijing, China.ORCID https://orcid.org/0000-0002-8317-1774

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During a spaceflight, astronauts need to live in a spacecraft on orbit for a long time, and the relationship between humans and microorganisms in the closed environment of space is not the same as on the ground. The dynamic study of microorganisms in confined space shows that with the extension of the isolation time, harmful bacteria gradually accumulate. Monitoring and controlling microbial pollution in a confined environment system are very important for crew health and the sustainable operation of a space life support system. Culture-based assays have been used traditionally to assess the microbial loads in a spacecraft, and uncultured-based techniques are already under way according to the NASA global exploration roadmap. High-throughput sequencing technology has been used generally to study the communities of the environment and human on the ground and shows its broad prospects applied onboard. We here review the recent application of high-throughput sequencing on space microbiology and analyze its feasibility and potential as an on-orbit detection technology.

Indexed as

High-Throughput Nucleotide SequencingMicrobiologySpace FlightHumansNanopore Sequencing

Identifiers

PMID32685480
PMCPMC7327617

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.