Evidence map›Paper›PMID 32685478›Full record

ArticleBioMed research international2020

Beneficial Effects of Crocin against Depression via Pituitary Adenylate Cyclase-Activating Polypeptide.

Linyu Lu, Die Wu, Kai Wang, Juanjuan Tang, Gang Chen

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Current pharmaceutical design · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. FermentedInternational journal of molecular sciences · 2022
    Article
  7. Review
  8. Review
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Linyu LuSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID https://orcid.org/0000-0003-0520-8444
Die WuSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID https://orcid.org/0000-0002-8536-8095
Kai WangSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID https://orcid.org/0000-0001-7204-4422
Juanjuan TangSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID https://orcid.org/0000-0002-1397-8687
Gang ChenInterdisciplinary Institute for Personalized Medicine in Brain Disorders, and Research Center for Formula and Syndromes, Jinan University, Guangzhou 510632, China.ORCID https://orcid.org/0000-0002-3507-1218
Nanjing University of Chinese Medicine · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is one of the foremost psychological illness, and the exact mechanism is unclear. Recent studies have reported that the pituitary adenylate cyclase-activating polypeptide (PACAP) signaling pathway is involved in the progression of depression. In the present study, we extracted crocin from the traditional Chinese medicine (TCM),

Indexed as

AnimalsBehavior, AnimalBody WeightCarotenoidsChronic DiseaseCorticosteroneCyclic AMP Response Element-Binding ProteinDepressionExtracellular Signal-Regulated MAP KinasesMaleMice, Inbred BALB CModels, BiologicalNeuroprotective AgentsPC12 CellsPhosphorylationPituitary Adenylate Cyclase-Activating PolypeptideCarotenoidsCorticosteronecrocinCyclic AMP Response Element-Binding ProteinExtracellular Signal-Regulated MAP KinasesNeuroprotective AgentsPituitary Adenylate Cyclase-Activating Polypeptide

Identifiers

PMID32685478
PMCPMC7334775
OpenAlexW3037491078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.