Evidence map›Paper›PMID 32685449›Full record

ArticleBioMed research international2020

Evaluation of Xpert MTB/RIF for the Diagnosis of Lymphatic Tuberculosis.

Hou-He Li, Zhi-Jian He, Jia-Qi Liang, Gui-Lin Li, Tian-Ao Xie, Ye-Ling Liu, Zhong-Wei Li, Xuan-Cheng Feng, Yong Xia, Xu-Guang Guo

Open access · hybridAbstract read
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Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hou-He Li *Department of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou 511436, China.
Zhi-Jian He *Department of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou 511436, China.
Jia-Qi LiangDepartment of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou 511436, China.
Gui-Lin LiNanshan School, Guangzhou Medical University, Guangzhou 511436, China.
Tian-Ao XieDepartment of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou 511436, China.
Ye-Ling LiuDepartment of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou 511436, China.
Zhong-Wei LiDepartment of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou 511436, China.
Xuan-Cheng FengDepartment of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou 511436, China.
Yong XiaDepartment of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou 511436, China.
Xu-Guang GuoDepartment of Clinical Medicine, The Third Clinical School of Guangzhou Medical University, Guangzhou 511436, China.ORCID https://orcid.org/0000-0003-1302-5234
Third Affiliated Hospital of Guangzhou Medical University · CNGuangdong Province Stomatological Hospital · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe World Health Organization approved the use of Xpert MTB/RIF for the detection of MATERIALS AND

methodsWe searched four databases for the relevant literature published from May 2007 to December 2019. The quality of the literature was evaluated with reference to the evaluation criteria. Data that were extracted from the literature on Xpert MTB/RIF diagnosis of lymphatic tuberculosis were used to plot the summary receiver operating characteristic (SROC) curve, after which the software was used to combine and analyze the accuracy of these data.

resultsA total of 27 studies were included. The sensitivity of Xpert MTB/RIF for detecting lymphatic tuberculosis was 0.79 (95% CI (0.77, 0.81)), the specificity was 0.88 (95% CI (0.87, 0.90)), and the positive likelihood ratio (PLR) was 7.21 (95% CI (4.93, 10.55)). In addition, the negative likelihood ratio (NLR) was 0.25 (95% CI (0.19, 0.32)) and the diagnostic odds ratio (DOR) was 40.23 (95% CI (24.53, 65.98)). At the same time, we used the extracted data to make the SROC curve, obtaining the following parameters: area under the curve (AUC) = 0.9144,

conclusionXpert MTB/RIF has high accuracy in detecting lymphatic tuberculosis, and it can be used to quickly and easily diagnose lymphatic tuberculosis at an early stage as a general method.

Indexed as

HumansMicrobial Sensitivity TestsMycobacterium tuberculosisNucleic Acid Amplification TechniquesPublication BiasRifampinROC CurveTuberculosisRifampin

Identifiers

PMID32685449
PMCPMC7338981
OpenAlexW3037057343

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.