ArticleJournal of reproduction & infertility
Distribution of Human Papillomavirus and Antisperm Antibody in Semen and Its Association with Semen Parameters Among Infertile Men.
Article in Journal of reproduction & infertility. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Potential causes and associated conditions with anti-sperm antibody production among infertile males: a systematic literature review.BMC immunology · 2025Pooled it
- Is HPV the Novel Target in Male Idiopathic Infertility? A Systematic Review of the Literature.Frontiers in endocrinology · 2021Pooled it
- Unfolding the Semen Microbiota: Implications for Male Infertility.Biomedicines · 2026Review
- Testicular immunity.Molecular aspects of medicine · 2024Review
- Human papillomavirus and male infertility correlation analysis following World Health Organization 2021 guidelines.Scientific reports · 2024Article
- Correlation between viral infections in male semen and infertility: a literature review.Virology journal · 2024Review
- Update on known and emergent viruses affecting human male genital tract and fertility.Basic and clinical andrology · 2024Review
- Molecular study of the presence and transcriptional activity of HPV in semen.Journal of endocrinological investigation · 2024Article
- Unraveling the Intricacies of the Seminal Microbiome and Its Impact on Human Fertility.Biology · 2024Review
- HPV-related diseases in male patients: an underestimated conundrum.Journal of endocrinological investigation · 2024Review
- Human Papillomavirus and Male Infertility: What Do We Know?International journal of molecular sciences · 2023Review
- Effects of COVID-19 Infection on Spermatogenesis, Oxidative Stress and Erectile Function.Journal of clinical medicine · 2023Article
- Human Papillomavirus (HPV) Infection and Its Impact on Male Infertility.Life (Basel, Switzerland) · 2022Article
- Human seminal virome: a panel based on recent literature.Basic and clinical andrology · 2022Review
- ORF8 protein of SARS-CoV-2 reduces male fertility in mice.Journal of medical virology · 2022Article
- Antisperm Antibody Testing: A Comprehensive Review of Its Role in the Management of Immunological Male Infertility and Results of a Global Survey of Clinical Practices.The world journal of men's health · 2022Review
- Pathogenesis of Autoimmune Male Infertility: Juxtacrine, Paracrine, and Endocrine Dysregulation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021Review
- Association between Human Papillomavirus and Chlamydia trachomatis genital infections in male partners of infertile couples.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSexually transmitted infections (STIs) can be associated with infertility. Human papillomavirus (HPV) has been identified as a potential agent in male infertility. Also, anti-sperm antibodies (ASA) have been detected in men with infertility. The aim of this study was to investigate the prevalence and association of HPV and ASA in infected semen of infertile men.
methodsThis cross-sectional study was performed on 96 infertile men referring to infertility treatment center of Kashan University of Medical Sciences during March 2017 till September 2017 in Iran. Semen analysis and diagnostic PCR test were performed for detection of HPV DNA. The semen parameters in HPV infected and ASA positive samples were compared with HPV non-infected and ASA negative samples. Chi square test was used to determine the correlation between variables and p<0.05 was considered statistically significant.
resultsHPV DNA and ASA were detected in 17.4% and 15.2% of 96 semen samples, respectively. Semen volume, sperm count, sperm motility and the normal morphology rate were significantly decreased in HPV-positive subjects (p=0.004, p= 0.016, p<0.001, and p=0.017, respectively). Also, sperm motility was significantly decreased in ASA-positive subjects (p=0.002), also patients with HPV infection had a higher rate of ASA than the non-HPV group. In contrast to ASA, HPV infection had a significant correlation with education level (p=0.039).
conclusionThe findings suggest that asymptomatic seminal infection of HPV and ASA by adversely affecting sperm quality, in particular sperm motility and count, may play an important role in male infertility.
Indexed as
Identifiers
32685415PMC7362092W3044853684What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.