Evidence map›Paper›PMID 32685412›Full record

ReviewJournal of reproduction & infertility

Coronavirus Disease 2019 (COVID-19): A Systematic Review of Pregnancy and the Possibility of Vertical Transmission.

Mohammad Ali Ashraf, Pedram Keshavarz, Parisa Hosseinpour, Amirhossein Erfani, Amirhossein Roshanshad, Alieh Pourdast, Peyman Nowrouzi-Sohrabi, Shahla Chaichian, Tahereh Poordast

Open access · greenAbstract readReview
PubMed Full text at PMC
In one paragraph

Review in Journal of reproduction & infertility. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 12 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 12 syntheses or guidelines pooled it, 103 citations in OpenAlex.

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  16. COVID-19's Effect in Pregnancy and Vertical Transmission: A Systematic Review.International journal of preventive medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mohammad Ali AshrafStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Pedram KeshavarzDepartment of Radiology, Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Parisa HosseinpourSchool of Medicine, Islamic Azad University, Kazeroun branch, Kazeroun, Iran.
Amirhossein ErfaniStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Amirhossein RoshanshadStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Alieh PourdastDepartment of infectious diseases, Tehran University of Medical Sciences, Tehran, Iran.
Peyman Nowrouzi-SohrabiDepartment of Biochemistry, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Shahla ChaichianPars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.
Tahereh PoordastDepartment of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IRIranian Center for Quantum Technologies · IRIran University of Medical Sciences · IRIslamic Azad University Kazeron · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a growing need for information regarding maternal and neonatal outcomes during coronavirus pandemic. In this study, a comprehensive investigation was done regarding the possibility of vertical transmission using the available data in the literature.

methodsA systematic search was conducted using electronic databases, including PubMed, Scopus, Web of Science, Embase, and Scholar. All studies containing infected COVID-19 pregnant women who had given birth were included, and the search was done up to April 14, 2020.

resultsOverall, 21 articles were reviewed, and clinical characteristics of 90 pregnant patients and 92 neonates born to mothers infected with COVID-19 were reviewed. The most common symptoms included fever, cough, and dyspnea. The main laboratory findings included leukocytosis, lymphopenia, thrombocytopenia, and elevated C-reactive protein. The most commonly reported complications were preterm labor and fetal distress. Three mothers were admitted to ICU and required mechanical ventilation; among them, one died, and one was on extracorporeal membrane oxygenation. Overall, 86 neonates were tested for the possibility of vertical transmission and 82 cases were negative in RT-PCR, while 4 were positive. Out of 92 neonates, one died, and one was born dead. Nineteen patients reported having no symptoms, while breathing problems and pneumonia were reported as the most common neonatal complications.

conclusionThere were no differences in the clinical characteristics of pregnant women and non-pregnant COVID-19 patients. COVID-19 infection has caused higher incidence of fetal distress and premature labor in pregnant women. Although the possibility of vertical transmission in infected pregnant women is rare, four neonates' test results for COVID-19 infection were positive in this review.

Indexed as

Coronavirus Disease 2019 (COVID-19)Neonatal outcomesPregnancyPregnant womenSARS-CoV-2Systematic reviewVertical transmission

Identifiers

PMID32685412
PMCPMC7362089
OpenAlexW3044277650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.