Evidence map›Paper›PMID 32685404›Full record

ArticleInternational journal of ophthalmology2020

Changes of lactate dehydrogenase in corneal edema after cataract surgery treated with trans-corneal oxygenation therapy.

Eunike Amelina Lahagu, Jajah Fachiroh, Andreas Surya Anugrah, Wasisdi Gunawan, Indra Tri Mahayana, Suhardjo

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eunike Amelina LahaguDepartment of Ophthalmology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada-Dr.Sardjito General Hospital, Yogyakarta 55284, Indonesia.
Jajah FachirohDepartment of Biomolecular and Cell Biology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55284, Indonesia.
Andreas Surya AnugrahDepartment of Ophthalmology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada-Dr.Sardjito General Hospital, Yogyakarta 55284, Indonesia.
Wasisdi GunawanDepartment of Ophthalmology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada-Dr.Sardjito General Hospital, Yogyakarta 55284, Indonesia.
Indra Tri MahayanaDepartment of Ophthalmology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada-Dr.Sardjito General Hospital, Yogyakarta 55284, Indonesia.
SuhardjoDepartment of Ophthalmology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada-Dr.Sardjito General Hospital, Yogyakarta 55284, Indonesia.
Universitas Gadjah Mada · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the changes in levels of the lactate dehydrogenase (LDH) enzyme in corneal edema after cataract surgery with trans-corneal oxygenation therapy.

methodsThis pre-post design study design conducted on 15 patients with corneal edema after cataract surgery and receiving trans-corneal oxygenation therapy. Tear sample (using Schirmer paper, from the inferior fornix of the conjunctiva) was carried out prior to trans-corneal oxygenation therapy, on the day 2 (D2) and day 5 (D5) postoperatively before and after trans-corneal oxygenation therapy. Visual acuity [VA (LogMAR)], corneal endothelial density, central corneal thickness (CCT), and coefficient of variation corneal endothelial (CoV) were recorded. The value of LDH was measured using ELISA. The difference in mean LDH value before and after trans-corneal oxygenation therapy, between two groups were analyzed using Wilcoxon signed rank test.

resultsThere was a decrease in LDH tear concentration at D2 (pre

conclusionTrans-corneal oxygenation therapy is associated with significant decrease of tears LDH levels in post cataract surgery with corneal edema. It is accompanied by clinical improvement such as significant reduction of CCT.

Indexed as

central corneal thicknesscorneal edema after cataract surgerylactate dehydrogenasetrans-corneal oxygenation

Identifiers

PMID32685404
PMCPMC7321936
OpenAlexW3037398670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.