Evidence map›Paper›PMID 32685188›Full record

ArticleClinical diabetes and endocrinology2020

Homozygous

Utku Erdem Soyaltin, Ilgin Yildirim Simsir, Baris Akinci, Canan Altay, Suleyman Cem Adiyaman, Kristen Lee, Huseyin Onay, Elif Arioglu Oral

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical diabetes and endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Lipodystrophic Laminopathies: From Dunnigan Disease to Progeroid Syndromes.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Utku Erdem SoyaltinDivision of Endocrinology and Metabolism, Department of Internal Medicine, Ege University, Izmir, Turkey.
Ilgin Yildirim SimsirDivision of Endocrinology and Metabolism, Department of Internal Medicine, Ege University, Izmir, Turkey.
Baris AkinciDivision of Endocrinology and Metabolism, Department of Internal Medicine, Dokuz Eylul University, Izmir, Turkey.
Canan AltayDepartment of Radiology, Dokuz Eylul University, Izmir, Turkey.
Suleyman Cem AdiyamanDivision of Endocrinology and Metabolism, Department of Internal Medicine, Dokuz Eylul University, Izmir, Turkey.
Kristen LeeDivision of Genetics, Metabolism & Genomic Medicine, Department of Pediatrics, Ann Arbor, MI USA.
Huseyin OnayDepartment of Medical Genetics, Ege University, Izmir, Turkey.
Elif Arioglu OralDivision of Metabolism, Endocrinology and Diabetes (MEND), Department of Internal Medicine, University of Michigan, Ann Arbor, MI USA.ORCID 0000-0002-9171-1144
Dokuz Eylül University · TREge University · TRCenter for Genomic Science · ITUniversity of Michigan · US

Funding

Mechanisms of adipocyte loss in laminopathy-induced lipodystrophy in mice and humansR01DK125513 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ormond A MacDougald, Elif Arioglu Oral · 2020 to 2026
$3.0M
NIDDK NIH HHS R01 DK125513
6 · The paper itself

Abstract

backgroundClassical heterozygous pathogenic variants of the lamin A/C ( CASE PRESENTATION: Here, we report a patient with a lamin A specific pathogenic variant in exon 11, denoted

conclusionsOur observations and radiological comparisons demonstrate an additive effect of

Indexed as

Generalized lipodystrophyHomozygousLamin ALMNAPartial lipodystrophy

Identifiers

PMID32685188
PMCPMC7362519
OpenAlexW3043438786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.