Evidence map›Paper›PMID 32685088›Full record

ArticleOxidative medicine and cellular longevity2020

Hexachloronaphthalene Induces Mitochondrial-Dependent Neurotoxicity via a Mechanism of Enhanced Production of Reactive Oxygen Species.

Malwina Lisek, Joanna Stragierowicz, Feng Guo, Philipp P Prosseda, Magdalena Wiktorska, Bozena Ferenc, Anna Kilanowicz, Ludmila Zylinska, Tomasz Boczek

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Strategies for Biomaterial-Based Spinal Cord Injury RepairFrontiers in bioengineering and biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Malwina LisekDepartment of Molecular Neurochemistry, Medical University of Lodz, 92215 Lodz, Poland.ORCID https://orcid.org/0000-0003-3438-2396
Joanna StragierowiczDepartment of Toxicology, Medical University of Lodz, 90151 Lodz, Poland.ORCID https://orcid.org/0000-0003-1137-8239
Feng GuoDepartment of Pharmaceutical Toxicology, China Medical University, Shenyang 110122, China.
Philipp P ProssedaDepartment of Patho Biochemistry, Goethe Universitätsklinikum, 60590 Frankfurt am Main, Germany.
Magdalena WiktorskaDepartment of Molecular Cell Mechanisms, Medical University of Lodz, 92215 Lodz, Poland.
Bozena FerencDepartment of Molecular Neurochemistry, Medical University of Lodz, 92215 Lodz, Poland.
Anna KilanowiczDepartment of Toxicology, Medical University of Lodz, 90151 Lodz, Poland.
Ludmila ZylinskaDepartment of Molecular Neurochemistry, Medical University of Lodz, 92215 Lodz, Poland.ORCID https://orcid.org/0000-0002-3876-8942
Tomasz BoczekDepartment of Molecular Neurochemistry, Medical University of Lodz, 92215 Lodz, Poland.ORCID https://orcid.org/0000-0002-7654-9011
Medical University of Lodz · PLChina Medical University · CNGoethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hexachloronaphthalene (PCN67) is one of the most toxic among polychlorinated naphthalenes. Despite the known high bioaccumulation and persistence of PCN67 in the environment, it is still unclear to what extent exposure to these substances may interfere with normal neuronal physiology and lead to neurotoxicity. Therefore, the primary goal of this study was to assess the effect of PCN67 in neuronal

Indexed as

AnimalsCell Culture TechniquesCell DifferentiationHumansMitochondriaNaphthalenesNerve DegenerationPC12 CellsRatsRats, Sprague-DawleyReactive Oxygen Species1,2,3,4,5,6-hexachloronaphthaleneNaphthalenesReactive Oxygen Species

Identifiers

PMID32685088
PMCPMC7335409
OpenAlexW3037681207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.