ArticleActa endocrinologica (Bucharest, Romania : 2005)
Craniopharyngiomas in children - experience of consecutive 152 operated cases.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Multidisciplinary Management of Pediatric Craniopharyngioma: From Diagnosis to Long-Term Outcomes.Biomedicines · 2026Review
- Article
- Evaluation of postoperative fluctuations in plasma sodium concentration and triphasic response after pediatric craniopharyngioma resection: A French cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- [Safety considerations for the clinical application of recombinant human growth hormone].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Review
- Intrinsic Third Ventricular Papillary Craniopharyngioma: A Report of Five Cases and Literature Review.International medical case reports journal · 2021Article
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5 authors.
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Abstract
contextCraniopharyngiomas (CPH) are benign tumors, rarely encountered in children, representing 5-6% of all intracranial tumors.
objectiveThis study aimed to analyze the surgical management and quality of life in a series of CPH pediatric cases.
designThis was a multicenter study performed over a 25-year period (1994 - 2019) in Bucharest. SUBJECTS AND
methods152 children (0-17 years old) were treated for CPH. Preoperative manifestations were intracranial hypertension, endocrine dysfunction, visual impairment, ataxia, intellectual performance decrease.
resultsConsidering all surgical approaches used, we advocate for pterional approach to best fit in CPH. We achieved gross-total removal (GTR) in 83 cases (54.4%), near-total resection (NTR) in 13 cases (9%), partial resection (PTR) in 51 cases (33.3%). 5 cases were biopsies (3.2%). Gamma Knife Surgery was performed in 10 cases (6.5%), all recurrences. At 6 months GOS revealed: Good Recovery 70 cases (46.2%), Moderate Disability 62 cases (40.7%), Severe Disability 13 (8.5%), Vegetative State 2 cases (1.3%), Deceased 5 cases (3.2%). Complications were: diabetes insipidus (89.3%); hypopituitarism (66.4%); hypothalamic damage (17.7%); visual deterioration (18.4%).
conclusionsSurgery remains the main option, but GTR complications prove the necessity for a multidisciplinary approach. Outcome predicting factors are: age, tumor size, hydrocephalus degree, hypothalamic dysfunction.
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