Evidence map›Paper›PMID 32685025›Full record

ArticleTheranostics2020

Protective effect of Soluble Epoxide Hydrolase Inhibition in Retinal Vasculopathy associated with Polycystic Kidney Disease.

Jihong Lin, Jiong Hu, Andrea Schlotterer, Jing Wang, Matthias Kolibabka, Khader Awwad, Nadine Dietrich, Kristin Breitschopf, Paulus Wohlfart, Aimo Kannt and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Jihong Lin5th Medical Department, Medical Faculty Mannheim, University of Heidelberg, D-68167 Mannheim, Germany.
Jiong HuInstitute for Vascular Signalling, Center for Molecular Medicine, Goethe University, D-60590 Frankfurt, Germany.
Andrea Schlotterer5th Medical Department, Medical Faculty Mannheim, University of Heidelberg, D-68167 Mannheim, Germany.
Jing Wang5th Medical Department, Medical Faculty Mannheim, University of Heidelberg, D-68167 Mannheim, Germany.
Matthias Kolibabka5th Medical Department, Medical Faculty Mannheim, University of Heidelberg, D-68167 Mannheim, Germany.
Khader AwwadInstitute for Vascular Signalling, Center for Molecular Medicine, Goethe University, D-60590 Frankfurt, Germany.
Nadine Dietrich5th Medical Department, Medical Faculty Mannheim, University of Heidelberg, D-68167 Mannheim, Germany.
Kristin BreitschopfSanofi Research and Development, Industriepark Hoechst, D-65926 Frankfurt, Germany.
Paulus WohlfartSanofi Research and Development, Industriepark Hoechst, D-65926 Frankfurt, Germany.
Aimo KanntSanofi Research and Development, Industriepark Hoechst, D-65926 Frankfurt, Germany.
Katrin LorenzSanofi Research and Development, Industriepark Hoechst, D-65926 Frankfurt, Germany.
Yuxi FengInstitute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty Mannheim, University of Heidelberg, D-68169 Mannheim, Germany.
Rüdiger PoppInstitute for Vascular Signalling, Center for Molecular Medicine, Goethe University, D-60590 Frankfurt, Germany.
Sigrid HoffmannCenter of Medical Research, Medical Faculty Mannheim, University of Heidelberg, D-68167 Mannheim, Germany.
Ingrid FlemingInstitute for Vascular Signalling, Center for Molecular Medicine, Goethe University, D-60590 Frankfurt, Germany.
Hans Peter Hammes5th Medical Department, Medical Faculty Mannheim, University of Heidelberg, D-68167 Mannheim, Germany.
Goethe University Frankfurt · DESanofi (Germany) · DEHeidelberg University · DEUniversity Medical Centre Mannheim · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDisease Models, AnimalEpoxide HydrolasesFatty Acids, UnsaturatedHumansMaleMicrogliaPolycystic Kidney DiseasesRatsRats, TransgenicRetinaRetinal DegenerationRetinal VesselsTRPP Cation Channels19,20-dihydroxydocosapentaenoic acidEPHX2 protein, ratEpoxide HydrolasesFatty Acids, UnsaturatedTRPP Cation Channels1920-DHDPCD74neurovascular unitretinal vasoregressionsEH inhibition

Identifiers

PMID32685025
PMCPMC7359083
OpenAlexW3040231884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.