Evidence map›Paper›PMID 32685000›Full record

ArticleTheranostics2020

Early Ultrafast Ultrasound Imaging of Cerebral Perfusion correlates with Ischemic Stroke outcomes and responses to treatment in Mice.

Vincent Hingot, Camille Brodin, Florent Lebrun, Baptiste Heiles, Audrey Chagnot, Mervé Yetim, Maxime Gauberti, Cyrille Orset, Mickael Tanter, Olivier Couture and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 58 citations in OpenAlex.

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  13. Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats - Comparison between ultrafast ultrasound and dynamic susceptibility contrast-enhanced MRI measurements.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  14. Commentary to Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  15. Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Vincent HingotInstitute Physics for Medicine Paris, Inserm U1273, ESPCI Paris, CNRS FRE 2031, PSL University.
Camille BrodinNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Caen, France.
Florent LebrunNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Caen, France.
Baptiste HeilesInstitute Physics for Medicine Paris, Inserm U1273, ESPCI Paris, CNRS FRE 2031, PSL University.
Audrey ChagnotNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Caen, France.
Mervé YetimNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Caen, France.
Maxime GaubertiCHU Caen, Department of radiology, Caen University Hospital, Avenue de la Côte de Nacre, Caen, France.
Cyrille OrsetNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Caen, France.
Mickael TanterInstitute Physics for Medicine Paris, Inserm U1273, ESPCI Paris, CNRS FRE 2031, PSL University.
Olivier CoutureInstitute Physics for Medicine Paris, Inserm U1273, ESPCI Paris, CNRS FRE 2031, PSL University.
Thomas DeffieuxInstitute Physics for Medicine Paris, Inserm U1273, ESPCI Paris, CNRS FRE 2031, PSL University.
Denis VivienNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Caen, France.
Physique pour la médecine ParisInserm · FRCentre Hospitalier Universitaire de Caen · FRCyceron · FRInstitut Langevin · FRLaboratoire d’Imagerie Biomédicale · FRNormandie Université · FRPhysiopathologie et imagerie des troubles neurologiquesUniversité de Caen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the field of ischemic cerebral injury, precise characterization of neurovascular hemodynamic is required to select candidates for reperfusion treatments. It is thus admitted that advanced imaging-based approaches would be able to better diagnose and prognose those patients and would contribute to better clinical care. Current imaging modalities like MRI allow a precise diagnostic of cerebral injury but suffer from limited availability and transportability. The recently developed ultrafast ultrasound could be a powerful tool to perform emergency imaging and long term follow-up of cerebral perfusion, which could, in combination with MRI, improve imaging solutions for neuroradiologists.

Indexed as

Cerebrovascular CirculationAnimalsBrainDisease Models, AnimalFibrinolytic AgentsHumansIntravital MicroscopyMagnetic Resonance ImagingMaleMiceMiddle Cerebral ArteryProof of Concept StudyRecombinant ProteinsThrombolytic TherapyThrombotic StrokeTime FactorsFibrinolytic AgentsRecombinant ProteinsTissue Plasminogen ActivatorIschemic strokeOutcomeThrombolysisUltrasound ImagingUltrasound Localization Microscopy

Identifiers

PMID32685000
PMCPMC7359089
OpenAlexW3038945074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.