ArticleNutrition & metabolism2020
Vitamin D status affects the relationship between lipid profile and high-sensitivity C-reactive protein.
Article in Nutrition & metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Vitamin D and biomarkers of inflammation and oxidative stress among pregnant women: a systematic review of observational studies.BMC immunology · 2023Pooled it
- Vitamin D supplementation for cardiometabolic risk markers in pregnant women based on the gestational diabetes mellitus or obesity status : a randomized clinical trial.European journal of nutrition · 2024Trial
- Association of hs-CRP/HDL, AIP and NHHR with chronic obstructive pulmonary disease: a cross-sectional NHANES study.Annals of medicine · 2025Article
- Alterations in the Metabolic and Lipid Profiles Associated with Vitamin D Deficiency in Early Pregnancy.Nutrients · 2025Article
- Mendelian Randomization Study on hs-CRP and Dyslipidemia in Koreans: Identification of Novel SNP rs76400217.International journal of molecular sciences · 2025Article
- The predictive role of the hs-CRP/HDL-C ratio for long-term mortality in the general population: evidence from a cohort study.BMC cardiovascular disorders · 2024Article
- Exploring the Relationship between Lipid Profile, Inflammatory State and 25-OH Vitamin D Serum Levels in Hospitalized Patients.Biomedicines · 2024Article
- Review
- C-reactive protein as a novel biomarker for vitamin D deficiency in alopecia areata.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.BMC geriatrics · 2024Article
- Article
- Association between maternal lipid profiles and vitamin D status in second trimester and risk of LGA or SGA: a retrospective study.Frontiers in endocrinology · 2024Article
- Interactive effect of increased high sensitive C-reactive protein and dyslipidemia on cardiovascular diseases: a 12-year prospective cohort study.Lipids in health and disease · 2023Article
- Assessment of Vitamin D status and association with inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project.The American journal of clinical nutrition · 2023Article
- Association between the index of nutritional quality and lipid profile in adult women.Endocrinology, diabetes & metabolism · 2022Article
- Adequate 25(OH)D moderates the relationship between dietary inflammatory potential and cardiovascular health risk during the second trimester of pregnancy.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe biological pathways through which vitamin D is involved in the regulation of systemic inflammation remain largely unknown.
objectiveThe objective of this study was to evaluate the role of vitamin D status on the relationship between lipid profile and high-sensitivity C-reactive protein (hs-CRP) in pregnant women.
designSerum 25-hydroxyvitamin D (25(OH)D), hs-CRP, and indicators of lipid profiles (total cholesterol, TC; triglyceride, TG; high-density lipoprotein cholesterol, HDL-C; low-density lipoprotein cholesterol, LDL-C), were measured in 2479 pregnant women during the second trimester. Potential confounding including maternal sociodemographic characteristics, perinatal health status, diet, and lifestyle was prospectively collected. Multiple regression models and cubic models were used to evaluate the associations.
resultsThere was a significant non-linear relationship between lipid profile (TC, TG, HDL-C, LDL-C) and hs-CRP (
conclusionOur findings suggest that high levels of vitamin D during pregnancy may improve lipid profile levels and inhibit elevated hs-CRP induced by high lipid metabolism.
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