ReviewReproductive medicine and biology2020
Trophectoderm biopsy for preimplantation genetic test and technical tips: A review.
Review in Reproductive medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Double Zona Drilling for Trophectoderm Biopsy: A Safe Strategy When Inner Cell Mass Herniates.Diagnostics (Basel, Switzerland) · 2026Article
- MicroRNAs Secreted by the Embryo in Spent Culture Medium Can Regulate mRNAs Involved in Endometrial Receptivity, Embryo Attachment, and Invasion.International journal of molecular sciences · 2025Article
- The future of embryo engineering and fertility research in interdisciplinary collaboration.Frontiers in cell and developmental biology · 2025Review
- Factors affecting biochemical pregnancy loss (BPL) in preimplantation genetic testing for aneuploidy (PGT-A) cycles: machine learning-assisted identification.Reproductive biology and endocrinology : RB&E · 2024Observational
- Evolution of Minimally Invasive and Non-Invasive Preimplantation Genetic Testing: An Overview.Journal of clinical medicine · 2024Review
- Trophectoderm biopsy of blastocysts following IVF and embryo culture increases epigenetic dysregulation in a mouse model.Human reproduction (Oxford, England) · 2024Article
- Embryo Culture Medium Has No Impact on Mosaicism Rates: a Sibling Oocyte Study.Reproductive sciences (Thousand Oaks, Calif.) · 2023Observational
- A novel embryo biopsy morphological analysis and genetic integrality criterion system significantly improves the outcome of preimplantation genetic testing.Journal of assisted reproduction and genetics · 2023Article
- Mosaic results after preimplantation genetic testing for aneuploidy may be accompanied by changes in global gene expression.Frontiers in molecular biosciences · 2023Article
- An Update on Non-invasive Approaches for Genetic Testing of the Preimplantation Embryo.Current genomics · 2022Review
- Comment on the recent PGDIS Position Statement on the Transfer of Mosaic Embryos 2021.Journal of assisted reproduction and genetics · 2022Article
- The Current Practice of Assisted Hatching for Embryos in Fertility Centres: a General Survey.Reproductive sciences (Thousand Oaks, Calif.) · 2022Article
- The effect of trophectoderm biopsy technique and sample handling on artefactual mosaicism.Journal of assisted reproduction and genetics · 2022Observational
- Article
- Application of Two Blastocyst Biopsy Strategies in Preimplantation Genetic Testing Treatment and Assessment of Their Effects.Frontiers in endocrinology · 2022Article
- Euploidy rates are not affected when embryos are cultured in a continuous (CCM) or sequential culture medium (SCM): a sibling oocyte study.Journal of assisted reproduction and genetics · 2021Observational
- Trophectoderm biopsy for preimplantation genetic test and technical tips: A review.Reproductive medicine and biology · 2020Review
- Fluid biopsies forMedicine internationalReview
- Impact of Inner Cell Mass Hatching Levels Before Vitrification on Clinical Pregnancy in Preimplantation Genetic Testing for Euploidy Cycles.Reproductive medicine and biologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecently, the Japan Society of Obstetrics and Gynecology initiated a clinical study of preimplantation genetic test for aneuploidy. There will be a great need for a standardized embryo biopsy technique in Japan. However, the gold standard trophectoderm (TE) biopsy procedure has not been established, and this review outlines the clinical use of TE biopsy.
methodsBased on literature, the method and associated techniques for TE biopsy, a dissection method of TE cells from blastocysts, were investigated. MAIN
findingsTwo TE biopsy methods are used, namely assisted hatching (herniating) and non-assisted hatching (direct suction); however, it is not clear which of these methods is superior. It is critical to understand whether the flicking or pulling method is beneficial.
conclusionNon-assisted hatching biopsy method may cause blastocyst collapse with a higher probability, and it may extend the biopsy time. The biopsy procedure should be performed within 3 minutes, and thus direct TE suction may have greater disadvantages. It is a fact that pulling method of TE dissection with laser pulse is simple; however, excess laser shots may induce a higher frequency of mosaicism. It is important to understand that each technique of TE biopsy has benefits and disadvantages.
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