Evidence map›Paper›PMID 32684646›Full record

ArticleReumatologia2020

The interrelationship of bone and cardiovascular remodeling biomarkers and clinical peculiarities of coronary artery disease in postmenopausal women.

Natalia Serhiivna Mykhailovska, Iryna Olehivna Stetsiuk, Tamila Olehivna Kulynych, Svitlana Vasylivna Gorbachova, Igor Valentynovych Zhulkevych

Open access · diamondAbstract read
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Article in Reumatologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Natalia Serhiivna MykhailovskaDepartment of General Practice - Family Medicine and Internal Diseases, Zaporizhzhia State Medical University, Zaporizhzhia, Ukraine.
Iryna Olehivna StetsiukDepartment of General Practice - Family Medicine and Internal Diseases, Zaporizhzhia State Medical University, Zaporizhzhia, Ukraine.
Tamila Olehivna KulynychDepartment of General Practice - Family Medicine and Internal Diseases, Zaporizhzhia State Medical University, Zaporizhzhia, Ukraine.
Svitlana Vasylivna GorbachovaDepartment of Clinical Laboratory Diagnostics, Zaporizhzhia State Medical University, Zaporizhzhia, Ukraine.
Igor Valentynovych ZhulkevychDepartment of Oncology, Radiodiagnosis, Radiotherapy and Radiation Medicine, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
Zaporizhia State Medical University · UAI.Horbachevsky Ternopil National Medical University · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the interrelationship between bone and cardiovascular remodeling biomarkers and some clinical, laboratory and instrumental parameters of coronary artery disease in postmenopausal women. MATERIAL AND

methodsThe double open cross-sectional monocentric clinical study in parallel groups involved 115 women in the postmenopausal period with coronary artery disease (CAD): stable exertional angina of functional class (FC) II-III (mean age 67.07 ±0.92 years). Depending on the bone mineral density (BMD) state, all patients were divided into 3 groups: group 1 (

resultsIn women with coronary artery disease and postmenopausal osteoporosis (PMO), there was a significant increase in the level of bone osteoprotegerin (OPG), osteocalcin and vascular remodeling biomarkers (VEGF-A, homocysteine) in parallel with the progression of BMD disorders. The existence of a correlative dependence between osteoprotegerin level and the 10-year risk of fracture of the radial bone (

conclusionsThe results obtained prove the existing interrelationship of bone and cardiovascular remodeling biomarkers with the state of bone mineral density and clinical peculiarities of coronary artery disease in postmenopausal women.

Indexed as

coronary artery diseasepostmenopausal osteoporosisprognostic factorsserum biomarkers

Identifiers

PMID32684646
PMCPMC7362271
OpenAlexW3042322033

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.