Evidence map›Paper›PMID 32684495›Full record

ArticlePain management nursing : official journal of the American Society of Pain Management Nurses2021

Policy Implications for Pain in Advanced Alzheimer's Disease.

Alison R Anderson, Karen Hyden, Michelle D Failla, Michael A Carter

Open access · greenAbstract read
In one paragraph

Article in Pain management nursing : official journal of the American Society of Pain Management Nurses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Experimentally evoked pain in Alzheimer's disease.Journal of the American Association of Nurse Practitioners · 2021
    Pooled it
  2. Article
  3. Dyadic Comparison of Pain and Stress in Alzheimer's Disease and Caregivers.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2025
    Article
  4. Mechanisms of comorbidity between Alzheimer's disease and pain.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  5. Article
  6. Article
  7. Pain and Associated Factors in Nursing Home Residents.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Policy Issues Affecting Nursing Pain Management: A New Decade of Hope.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Alison R AndersonVanderbilt University School of Nursing, Nashville, Tennessee. Electronic address: alison.r.anderson@vanderbilt.edu.
Karen HydenUniversity of Colorado Denver, Anschutz Medical Campus, Denver, Colorado.
Michelle D FaillaDepartment of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.
Michael A CarterUniversity of Tennessee Health Science Center College of Nursing, Memphis, Tennessee.
University of Colorado Anschutz Medical Campus · USUniversity of Tennessee Health Science Center · USVanderbilt University · USVanderbilt University Medical Center · US

Funding

LIFE-SPAN DEVELOPMENT OF NORMAL AND ABNORMAL BEHAVIORT32MH018921 · NIMH · VANDERBILT UNIVERSITY · PI HUMPHREYS, KATHRYN LEIGH · 1989 to 2024
$6.7M
NRSA Training CoreTL1TR002244 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$4.6M
Sex Differences in Pain Reports and Brain Activation in Older Adults with Alzheimers DiseaseR01AG059861 · NIA · OHIO STATE UNIVERSITY · PI MONROE, TODD BRYANT · 2018 to 2022
$3.6M
NCATS NIH HHS TL1 TR002244NIA NIH HHS R01 AG059861NIMH NIH HHS T32 MH018921
6 · The paper itself

Abstract

Untreated pain in people with Alzheimer's disease continues to be a serious public health problem. Pain is a subjective and complex experience that becomes increasingly challenging to assess as cognition declines. Our understanding of pain processing is incomplete, particularly for special populations such as people living with Alzheimer's disease, and especially in the advanced stages of the disease. Pain-processing networks in the brain are altered in Alzheimer's disease, yet evidence suggests people living with Alzheimer's disease do not experience less pain. Rather, their pain is not adequately recognized or treated. Although scholarly publications provide important assistance, recent widespread reports and guidelines do not include sufficient guidance, especially as Alzheimer's disease progresses to the last stages. Additionally, current pain measurements may not accurately evaluate pain in this condition, and the existing definitions of pain are not adequate when considering the effects of Alzheimer's disease on pain-processing in the brain. There is a need for new, widespread policies, guidelines, and definitions to help clinicians adequately manage pain in people with Alzheimer's disease. These will need to hinge on continued research because it remains unclear how Alzheimer's disease impacts central pain processing, pain expression, and communication of pain. In the meantime, policies and guidelines need to highlight current best practices as well as the fact that pain continues in Alzheimer's disease.

Indexed as

Alzheimer DiseasePainCognitionHumansPain MeasurementPolicy

Identifiers

PMID32684495
PMCPMC7854970
OpenAlexW3042343308

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.