ArticleStroke2020
Infarction of the Splenium of the Corpus Callosum in the Age of COVID-19: A Snapshot in Time.
Article in Stroke, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Heterogeneity in Regional Damage Detected by Neuroimaging and Neuropathological Studies in Older Adults With COVID-19: A Cognitive-Neuroscience Systematic Review to Inform the Long-Term Impact of the Virus on Neurocognitive Trajectories.Frontiers in aging neuroscience · 2021Pooled it
- COVID-19 and Cerebrovascular Diseases: A Systematic Review and Perspectives for Stroke Management.Frontiers in neurology · 2020Pooled it
- Article
- Diffusion-Restricted Lesions of the Splenium: Clinical Presentation, Radiographic Patterns, and Patient Outcomes.Neurology. Clinical practice · 2023Article
- Reversible splenial lesion after surgery for distant arteriovenous malformation: a case report.Acta neurochirurgica · 2023Article
- Article
- Persistent hiccups as main COVID-19 manifestation with transient cytotoxic lesion of the corpus callosum splenium during the Omicron wave in the post-vaccination era.Journal of neurology · 2023Article
- Mild Encephalitis/Encephalopathy with a Reversible Lesion in The Splenium.Noro psikiyatri arsivi · 2023Article
- Transient splenial lesions of the corpus callosum and infectious diseases.Acute and critical care · 2022Article
- COVID-19-Associated Stroke.Neuroscience and behavioral physiology · 2022Article
- Imaging findings of two patients with isolated infarction of the splenium during COVID-19.SAGE open medical case reports · 2022Article
- Neurological complications and infection mechanism of SARS-COV-2.Signal transduction and targeted therapy · 2021Review
- Intracranial microhemorrhages in the setting of COVID-19: what we know so far.The neuroradiology journal · 2021Review
- COVID-19: Neuroimaging Features of a Pandemic.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2021Review
- Article
- Severe Acute Respiratory Syndrome Coronavirus 2-Induced Neurological Complications.Frontiers in cell and developmental biology · 2020Review
- COVID-19 and cerebrovascular diseases: a comprehensive overview.Therapeutic advances in neurological disorders · 2020Review
- Diffusion Restricted Lesions in the Splenium of the Corpus Callosum.In vivo (Athens, Greece)Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeIschemic infarction of the corpus callosum is rare and infarction isolated to the corpus callosum alone rarer still, accounting for much <1% of ischemic stroke in most stroke registries. About half of callosal infarctions affect the splenium.
methodsDuring a 2-week period, at the height of the coronavirus disease 2019 (COVID-19) pandemic in New York City, 4 patients at Montefiore Medical Center in the Bronx were found to have ischemic lesions of the splenium of the corpus callosum, 2 with infarction isolated to the corpus callosum.
resultsAll patients tested positive for COVID-19 and 3 had prolonged periods of intubation. All had cardiovascular risk factors. Clinically, all presented with encephalopathy and had evidence of coagulopathy and raised inflammatory markers.
conclusionsInfarction of the splenium of the corpus callosum is exceedingly rare and a cluster of such cases suggests COVID-19 as an inciting agent, with the mechanisms to be elucidated.
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Registered trials
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