Worrying situation regarding the use of dexamethasone for COVID-19.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it.

1. Dipeptidyl peptidase-4 (DPP-IV) inhibitor was associated with mortality reduction in COVID-19 - A systematic review and meta-analysis.Primary care diabetes · 2022
   Pooled it
2. COVID-19, corticosteroids and public health: a reappraisal.Public health · 2021
   Pooled it
3. Active prescription of low-dose aspirin during or prior to hospitalization and mortality in COVID-19: A systematic review and meta-analysis of adjusted effect estimates.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
   Pooled it
4. Charlson comorbidity index and a composite of poor outcomes in COVID-19 patients: A systematic review and meta-analysis.Diabetes & metabolic syndrome
   Pooled it
5. Sivelestat protects against acute lung injury by up-regulating angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas receptors.Journal of thoracic disease · 2024
   Article
6. Lidocaine and Dexamethasone, Ketamine and Dexamethasone, and Dexamethasone Alone in Tonsillectomy Complications.Advanced biomedical research · 2024
   Article
7. Evolution of SARS-CoV-2 Variants: Implications on Immune Escape, Vaccination, Therapeutic and Diagnostic Strategies.Viruses · 2023
   Review
8. Effects of tocilizumab and dexamethasone on the downregulation of proinflammatory cytokines and upregulation of antioxidants in the lungs in oleic acid-induced ARDS.Respiratory research · 2022
   Article
9. Comments on "Whole lung irradiation as a novel treatment for COVID-19: Interim results of an ongoing phase 2 trial in India".Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2022
   Article
10. Lack of Correlation Between Soluble Angiotensin-Converting Enzyme 2 and Inflammatory Markers in Hospitalized COVID-19 Patients with Hypertension.Infection and drug resistance · 2022
    Article
11. Treatment of COVID-19 by stage: any space left for mesenchymal stem cell therapy?Regenerative medicine · 2021
    Review
12. Adverse Cardiovascular Effects of Anti-COVID-19 Drugs.Frontiers in pharmacology · 2021
    Review
13. Dreadful Consequences of Sarcopenia and Osteoporosis due to COVID-19 Containment.Geriatric orthopaedic surgery & rehabilitation · 2021
    Article
14. Dexamethasone to combat cytokine storm in COVID-19: Clinical trials and preliminary evidence.International journal of surgery (London, England) · 2020
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as