Evidence map›Paper›PMID 32683988›Full record

ArticleConnective tissue research2021

Blocking CCN2 preferentially inhibits osteoclastogenesis induced by repetitive high force bone loading.

Mary F Barbe, Mamta Amin, Anne Gingery, Alex G Lambi, Steven N Popoff

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Connective tissue research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. CCN proteins: opportunities for clinical studies-a personal perspective.Journal of cell communication and signaling · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mary F BarbeDepartment of Anatomy & Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.ORCID 0000-0002-5235-9803
Mamta AminDepartment of Anatomy & Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
Anne GingeryDepartment of Orthopedic Surgery, Indiana University School of Medicine , Indianapolis, IN, USA.
Alex G LambiDivision of Plastic & Reconstructive Surgery, University of California, Los Angeles David Geffen School of Medicine , Los Angeles, CA, USA.
Steven N PopoffDepartment of Anatomy & Cell Biology, Lewis Katz School of Medicine, Temple University , Philadelphia, PA, USA.
Temple University · USIndiana University School of MedicineUniversity of California, Los Angeles · US

Funding

Biomarkers of Tissue Tolerance and Behavior in a Rat ModelR01AR056019 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI BARBE, MARY F · 2009 to 2025
$7.3M
High-resolution ex vivo micro-computerized tomography systemS10RR026727 · NCRR · TEMPLE UNIV OF THE COMMONWEALTH · PI BARBE, MARY F · 2010 to 2010
$308k
NCRR NIH HHS S10 RR026727NIAMS NIH HHS R01 AR056019
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

OsteogenesisAnimalsAntibodies, MonoclonalConnective Tissue Growth FactorCumulative Trauma DisordersDisease Models, AnimalFemaleImmunoglobulin GRatsRats, Sprague-DawleyAntibodies, MonoclonalCCN2 protein, ratConnective Tissue Growth FactorImmunoglobulin GCTGFfibrosismusclemusculoskeletal disordersoveruse

Identifiers

PMID32683988
PMCPMC8189320
OpenAlexW3045460296

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.